The effect of three different doses of Chloroprocaine drug on spinal anesthesia urology surgical procedures

Not yet recruiting

• Conditions: Disorder of kidney and ureter, unspecified,

• Registration Number: CTRI/2020/06/025677
• Lead Sponsor: Dr Kavya D C

Brief Summary

Spinal anaesthesia has advantage over general anesthesia as it avoids problems

associated with intubation, postoperative nausea and vomiting, delayed postoperative oral

intake by the patient and increased duration of hospital stay for the patient. Spinal anaesthesia

is usually carried out with available local anesthetic agents like lignocaine and bupivacaine.

Transient Neurologic Symptoms (TNS) is reported with lignocaine and with bupivacaine there

is delay in the recovery of the motor block after anaesthesia and hence has prolonged time for

regression of the level of anaesthesia which can delay the mobility of the patient thereby

delaying the hospital discharge. Chloroprocaine has rapid onset of action and rapid offset and

less complications. Considering the above benefits it can be used in short duration urology

surgical procedures. Hence helpful in day care surgeries which reduce the cost, enhances early

ambulation and early discharge of patients from the hospital.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2020-01-06
• Study Start: 2020-08-06

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

American Society of Anaesthesiologists (ASA) physical status I , II and III BMI <35 Patients undergoing subarachnoid block in elective urological surgeries lasting for less than 60 minutes.

Exclusion Criteria

Patient refusal Patients with local infection at site of injection Patients with known or ascertained hypersensitivity to local anaesthesia Patient with coagulopathy, bleeding disorders and/or on treatment with anticoagulants History of neurological/psychiatric diseases Pregnant women and lactating women.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare the efficacy of intrathecal Chloroprocaine (1%) in three different doses for urology	1.5 years
surgical procedures.	1.5 years

Secondary Outcome Measures

Name	Time	Method
To estimate the time taken for readiness for surgery by achieving maximum sensory and motor blockade which can be known by pinprick sensation and Bromage scale more than or equal to 2 at the required metameric more than equal to T12	1.5 years
To estimate the time taken for unassisted ambulation which is a discharge criteria of patient from the hospital	1.5 years
To estimate the time taken for onset of motor block	1.5 years
To estimate the time taken for first postoperative analgesia	1.5 years
To estimate the time taken for the onset of sensory block	1.5 years

Trial Locations

Locations (1)

Sri Manakula Vinayagar Medical College and Hospital; 🇮🇳 Pondicherry, PONDICHERRY, India

Sri Manakula Vinayagar Medical College and Hospital

🇮🇳Pondicherry, PONDICHERRY, India

Dr Kavya D C

Principal investigator

9980182656

kavyadoddamane@gmail.com