The effect of three different doses of Chloroprocaine 1% on spinalanaesthesia in short duration elective urology surgical procedures– A randomized controlled trail.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- To compare the efficacy of intrathecal Chloroprocaine (1%) in three different doses for urology
研究概览
简要总结
Spinal anaesthesia has advantage over general anesthesia as it avoids problems
associated with intubation, postoperative nausea and vomiting, delayed postoperative oral
intake by the patient and increased duration of hospital stay for the patient. Spinal anaesthesia
is usually carried out with available local anesthetic agents like lignocaine and bupivacaine.
Transient Neurologic Symptoms (TNS) is reported with lignocaine and with bupivacaine there
is delay in the recovery of the motor block after anaesthesia and hence has prolonged time for
regression of the level of anaesthesia which can delay the mobility of the patient thereby
delaying the hospital discharge. Chloroprocaine has rapid onset of action and rapid offset and
less complications. Considering the above benefits it can be used in short duration urology
surgical procedures. Hence helpful in day care surgeries which reduce the cost, enhances early
ambulation and early discharge of patients from the hospital.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 70.00 Year(s)（—）
- 性别
- All
入选标准
- •American Society of Anaesthesiologists (ASA) physical status I , II and III BMI <35 Patients undergoing subarachnoid block in elective urological surgeries lasting for less than 60 minutes.
排除标准
- •Patient refusal Patients with local infection at site of injection Patients with known or ascertained hypersensitivity to local anaesthesia Patient with coagulopathy, bleeding disorders and/or on treatment with anticoagulants History of neurological/psychiatric diseases Pregnant women and lactating women.
结局指标
主要结局
To compare the efficacy of intrathecal Chloroprocaine (1%) in three different doses for urology
时间窗: 1.5 years
surgical procedures.
时间窗: 1.5 years
次要结局
- To estimate the time taken for readiness for surgery by achieving maximum sensory and motor blockade which can be known by pinprick sensation and Bromage scale more than or equal to 2 at the required metameric more than equal to T12(1.5 years)
- To estimate the time taken for unassisted ambulation which is a discharge criteria of patient from the hospital(1.5 years)
- To estimate the time taken for onset of motor block(1.5 years)
- To estimate the time taken for first postoperative analgesia(1.5 years)
- To estimate the time taken for the onset of sensory block(1.5 years)