Vitamin D3 Levels in COVID-19 Outpatients From Western Mexico

Not Applicable

Completed

• Conditions: Covid19
• Interventions: Dietary Supplement: Vitamin D3

• Registration Number: NCT04793243
• Lead Sponsor: University of Guadalajara

Brief Summary

The immunomodulatory effects of vitamin D are known to be beneficial in viral infections, it is also known that its deficiency is associated with a worse prognosis of COVID-19. This study aimed to determine the baseline vitamin D serum concentrations in asymptomatic or mildly symptomatic COVID-19 outpatients, as well as to evaluate the effects of supplementation with 10,00 IU/daily of vitamin D3 and its relationship with biochemical parameters and clinical features.

Detailed Description

Not available

Study Timeline

• Study Start: 2020-08-17
• Primary Completion: 2020-10-10
• Study Completion: 2020-10-24
• Status Verified: 2021-03
• Study First Submitted: 2021-03-03
• Study First Submitted QC: 2021-03-09
• Last Update Submitted: 2021-03-09
• Study First Posted: 2021-03-11
• Last Update Posted: 2021-03-11

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 42

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Intervention group	Vitamin D3	Formed by 22 patients that received oral supplementation of 10,000 IU daily for fourteen days of vitamin D3

Primary Outcome Measures

Name	Time	Method
Baseline levels of serum vitamin D in COVID-19 patients	At baseline	Evaluate serum levels of 25(OH)D (ng/mL) in patients with covid-19 from western Mexico
Correlation between transferrin and vitamin D serum levels in COVID-19 patients	At baseline	Serum levels of transferrin (mg/dL) will be measured at baseline and correlated with levels of 25(OH)D (ng/mL) in patients with covid-19 from western Mexico
Correlation between D-dimer and vitamin D serum levels in COVID-19 patients	At baseline	Serum levels of D-dimer (ng/mL) will be measured at baseline and correlated with levels of 25(OH)D (ng/mL) in patients with covid-19 from western Mexico
Correlation between ferritin and vitamin D serum levels in COVID-19 patients	At baseline	Serum levels of ferritin (ng/mL) will be measured at baseline and correlated with levels of 25(OH)D (ng/mL) in patients with covid-19 from western Mexico
Effects of vitamin D3 supplementation on COVID-19 patients	After 14 days of supplementation	Serum levels of 25(OH)D (ng/mL) will be determined in the intervention group after 14 days of Vitamin D3 supplementation

Trial Locations

Locations (1)

Universidad de Guadalajara; 🇲🇽 Guadalajara, Jalisco, Mexico