The study to evaluate the efficacy and safety of Polynucleotide on Acne Scars
Phase 4
Recruiting
- Conditions
- Acne scarPolynucleotide, Acne scar
- Registration Number
- TCTR20230213003
- Lead Sponsor
- SW HEALTHCARE CO.,LTD
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 27
Inclusion Criteria
1. Aged 18-60 years old
2. Both male and female
3. moderate to severe acne scar from global acne scar grading system
Exclusion Criteria
1. Subjects who are pregnant
2. Subjects who had history of low platelet, coagulopathy or taking medicine of antocoagulant drug like warfarin
3. Subjects who has dermatits, wound or infection at treatment area
4. Subjects who allergy to anesthesia cream
5. Subjects who taken oral or injection contraceptive pills
6. Subjects who had history of laser, filler and botox at treatment area within 12 months before arrived the project
7. Subjects who had history of keloid or hypertrophic scar
8. Subjects who had history of psychitic disease
9. Subjects who use tretinoin or AHA with in 1 months
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Average Wrinkle and Texture Baseline, 1 month after 1st treatment, 1 months after 2nd treatment, 1 month, 3 months, 6 months after the last treatments. Antera
- Secondary Outcome Measures
Name Time Method Skin elasticity Baseline, 1 month after 1st treatment, 1 months after 2nd treatment, 1 month, 3 months, 6 months after the last treatments. Cutometer,Melanin index Baseline, 1 month after 1st treatment, 1 months after 2nd treatment, 1 month, 3 months, 6 months after the last treatments. mexameter,Erythema Index Baseline, 1 month after 1st treatment, 1 months after 2nd treatment, 1 month, 3 months, 6 months after the last treatments. Mexameter,Physician improvement scale Baseline, 1 month after 1st treatment, 1 months after 2nd treatment, 1 month, 3 months, 6 months after the last treatments. Percent improvement,Patient improvement scale Baseline, 1 month after 1st treatment, 1 months after 2nd treatment, 1 month, 3 months, 6 months after the last treatments. percent improvement,safety Baseline,1 month after 1st treatment, 1 months after 2nd treatment and 2 week, 1,2,3,6 months after 3rd treatments adverse effect