Concentrated Growth Factors in Regenerative Therapy in Furcation Involvements in Humans
Not Applicable
- Conditions
- Periodontal RegenerationConcentrated Growth FactorsFurcation Defects
- Interventions
- Procedure: GTR + CGF + bone graftProcedure: CGF + bone graft
- Registration Number
- NCT03180658
- Lead Sponsor
- Jing Qiao
- Brief Summary
Objective: To compare the effect of guided tissue regeneration (GTR) + concentrated growth factors (CGF) + bone graft and CGF + bone graft in the treat of II° furcations of human mandibular molars. Methods: At least thirty II°furcation involvements in mandibular molars will be included and randomly divided into two groups. The experimental group will accept GTR + CGF + bone graft therapy, and the control group will accept CGF + bone graft therapy. The clinical examination and cone beam computed tomography (CBCT) will be performed at baseline and 1 year post-surgery.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
- II° furcation involvements in mandibular molars
- after periodontal therapy.
Exclusion Criteria
- not healthy
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description experimental GTR + CGF + bone graft GTR+CGF+bone graft, CGF controlled CGF + bone graft CGF+bone graft
- Primary Outcome Measures
Name Time Method clinical measurement 1 year Probing depth
clinical parameter 1 year clinical attachment loss
- Secondary Outcome Measures
Name Time Method radiographic parameter 1 year cone beam computerized tomographic scanning
Trial Locations
- Locations (1)
Peking university School and Hospital of Stomatology
🇨🇳Beijing, Beijing, China