Effect of healing outcomes of pulpotomy compared with root canal treatment in patients diagnosed with symptomatic irreversible pulpitis: A randomized controlled trial

The most common oral health issue is untreated dental caries in permanent teeth. Dental caries left untreated can result in the spread of bacteria and their toxins entering the dental pulp, inflaming it to varied degrees. In previous studies it has been observed that the underlying pulp continued to be free of inflammation even in advanced cases of inflammation with irreversible pulpitis, with only isolated portions of pulp in the coronal aspect experiencing bacterial invasion and micro abscesses. After excavation of infected coronal pulp tissue followed by restoration with biomimetic materials like MTA may prevent the further progress of infection. Thus, the vitality of the radicular pulp can be maintained. The Purpose of the current randomized controlled trial will be to assess the healing outcomes clinically and radiographically in adult patients diagnosed with symptomatic irreversible pulpitis. This is a prospective single blind (observer blind) open label trial. The post-operative pain levels and healing outcomes between Pulpotomy and RCT group will be assessed at baseline, 6 hours, 24 hours and 7 days post-operative time intervals and the data will be statistically analyzed using unpaired t-test (for parametric data) or Mann-Whitney U test (for non-parametric). Within group comparison for the post-operative pain levels between Pulpotomy and RCT group will be assessed at baseline, 6 hours, 24 hours and 7 days post- operative time intervals using repeated measure ANOVA and Tukey’s post-hoc (for parametric data) or Kruskal–Wallis ANOVA and Dunn’s post-hoc (for non-parametric).