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Study of E3810 for Healthy Japanese Male (Under Fasting Condition)

Phase 1
Completed
Conditions
Healthy
Interventions
Registration Number
NCT01085695
Lead Sponsor
Eisai Co., Ltd.
Brief Summary

The purpose of this study is to assess the pharmacokinetics of rabeprazole under fasting condition.

Detailed Description

The purpose of this study is to assess bioequivalence after single administration of the following 4 types of formulation: normal 10 mg rabeprazole tablet rabeprazole, and Type 1, Type 2, and Type 3 granule formulation containing rabeprazole 10 mg.

Recruitment & Eligibility

Status
COMPLETED
Sex
Male
Target Recruitment
16
Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

Study Type
INTERVENTIONAL
Study Design
CROSSOVER
Arm && Interventions
GroupInterventionDescription
1rabeprazole-
2rabeprazole-
3rabeprazole-
4rabeprazole-
Primary Outcome Measures
NameTimeMethod
The following pharmacokinetic parameters are calculated: maximum drug concentration (Cmax) in plasma; area under the plasma concentration time curve (AUC)One day
Secondary Outcome Measures
NameTimeMethod
Vital signs, clinical laboratory screens of blood and urine, adverse event monitoring, adverse drug reaction monitoring13 days
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