Comparison of Transurethral Split of the Prostate Versus Transurethral Resection of the Prostate for Treatment of Benign Prostatic Hyperplasia in a Small Prostate Volume: A Prospective Controlled Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Benign Prostatic Hyperplasia
- Sponsor
- Second Affiliated Hospital, School of Medicine, Zhejiang University
- Enrollment
- 150
- Locations
- 1
- Primary Endpoint
- international prostate symptoms score（IPSS）
- Last Updated
- 4 years ago
Overview
Brief Summary
Comparison of transurethral split of the prostate versus transurethral resection of the prostate for treatment of benign prostatic hyperplasia in a small prostate volume: A prospective controlled study
Detailed Description
Transurethral resection of the prostate (TURP) was considered as the golden standard to treat benign prostatic hyperplasia (BPH) for decades. However, TURP was associated with low efficiency to alleviate the lower urinary tract symptoms and a significantly higher risk of bladder neck contracture (BNC) for patients with small-volume BPH. We aimed to compare the therapeutic effect of transurethral split of the prostate (TUSP) with TURP for patients with small-volume BPH (\<30 ml). In this study, some selected small-volume BPH patients were randomly divided into two groups (TUSP and TURP group). The patient's baseline characteristics and perioperative outcomes were recorded. The follow-up was made at 6 months, 1 year and 2 years after surgical treatment.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Benign prostatic hyperplasia patients with surgical indication
- •Maximum flow rate \<12ml/s
- •Prostate volume \<30ml
- •The international prostate symptoms score\>21
- •Medication of α-adrenergic blockers for at least 3 months
Exclusion Criteria
- •Acute prostatitis and urethritis
- •Neurogenic bladder
- •Abnormal prostate-specific antigen level
- •Urethral injury history
Outcomes
Primary Outcomes
international prostate symptoms score（IPSS）
Time Frame: within 24 months after surgery
Measuring the International Prostate Symptoms Score by a questionnaire (which minimum value is zero and the maximum value is 35; higher scores mean a worse outcome)
maximum urinary flow rate（Qmax）
Time Frame: within 24 months after surgery
Measuring the maximum urinary flow rate by a urodynamic study