Omentum preservation versus complete omentectomy in gastrectomy for gastric cancer

Recruiting

• Conditions: gastric adenocarcinoma; Gastric cancer; 10017990; 10017998

• Registration Number: NL-OMON56599
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 554

Inclusion Criteria

- Primary resectable gastric adenocarcinoma, clinical stage T1-4aN0-3M0
- ASA 1-3 (able to undergo surgery)
- Scheduled for open or minimally invasive (sub)total gastrectomy with modified
D2-lymphadenectomy, with or without perioperative chemotherapy
- Age above 18 year
- Able to complete questionnaires in Dutch, English or Italian
- Written informed consent
- Esophageal invasion < 2 cm defined from the upper margin of the gastric rugae
as determined by endoscopy

Exclusion Criteria

- Gastric cancer clinically staged as T1N0
- Locally advanced gastric cancer requiring multi-visceral resection
- Pregnancy
- Previous malignancy (excluding non-melanoma skin cancer, pancreatic
neuroendocrine tumor (pNET) <2cm, and gastrointestinal stromal tumor (GIST)
<2cm), unless no evidence of disease and diagnosed more than three years before
diagnosis of gastric cancer, or with a life expectancy of more than five years
from date of inclusion
- Serious concomitant systemic disorders that would compromise the safety of
the patient or his/her ability to complete the study, at the discretion of the
investigator
- Previous gastric or omental surgery, with the exclusion of a gastric
perforation
- Indication for thoracotomy/thoracoscopy

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Overall survival at three-years after the operation, defined as the period of<br /><br>time between operation and death from any cause. Patients alive at last<br /><br>follow-up are censored.</p><br>