MedPath

Total Wrist Denervation: Survival Study and Functional Outcomes

Completed
Conditions
Survival
Wrist Arthritis
Interventions
Procedure: Total wrist denervation
Registration Number
NCT03977389
Lead Sponsor
University Hospital, Brest
Brief Summary

The purpose of the study is to evaluate the long-term effectiveness of total wrist denervation on pain by assessing the surgery survival.

The residual functional wrist's quality and the patients' satisfaction will also be evaluate.

Detailed Description

The degenerative diseases of the wrist are numerous and include both post-traumatic osteoarthritis lesions and inflammatory diseases. In any case, one of the main reasons for consultation is pain. In case of inefficiency of a well-conducted medical treatment (splints, anti-inflammatories, infiltrations), surgical management remains difficult because of the multitude of treatments that can be offered: partial or total arthrodesis of the wrist, prosthetic arthroplasties, pyrocarbon implants or proximal row carpectomy. But these treatments are heavy and can potentially be sources of complications such as stiffness, loss of strength or progressive wear of the implant.

Total wrist denervation is an alternative since 1966. The original technique follows an anatomical study of the innervation of the upper limb. This technique has been proven to significantly improve pain without major after effects. Several teams demonstrated a decrease in pain associated with conserved strength and mobility, but few studies have studied the long-term results of this technique, especially on the absence of residual pain.

The purpose of this study is to evaluate the long-term effectiveness of denervation on pain by assessing the surgery survival, the residual functional wrist's quality and the patients' satisfaction.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
63
Inclusion Criteria
  • patient undergoing total wrist denervation between January 1995 and December 2013 at Brest CHRU, performed by the same senior surgeon
Exclusion Criteria
  • patient who had another intervention at the same time (confounding factor)
  • refusal expressed by the patient to participate in the study

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Population of the studyTotal wrist denervationPatient undergoing total wrist denervation between January 1995 and December 2013 at Brest CHRU, performed by the same senior surgeon. Total wrist denervation is a routine procedure in orthopedic surgery for wrist arthritis.
Primary Outcome Measures
NameTimeMethod
survival over timefrom date of surgery until the date of first documented failure (surgical revision; pain > 3), assessed up to the inclusion date

duration (in years) of absence of surgical revision, and residual pain \< or = 3 on a pain numerical scale (0 to 10, WHO criteria for mild pain)

Secondary Outcome Measures
NameTimeMethod
patients' satsfaction (2)at the inclusion date

answer to "would you repeat this procedure again?"

surgery survival over timefrom date of surgery until the date of documented failure (surgical revision), assessed up to the inclusion date

duration (in years) of absence of surgical revision

residual functional wrist's qualityat the inclusion date

Result of the DASH (Disabilities of the Arm and Shoulder Disabilities) score (between 0 to 100; 0 equal better result; 100 equal worst result)

residual painat the inclusion date

numeric pain rating scale (between 0 to 10; 0 equal no pain; 10 equal "worst pain imaginable")

patients' satisfaction (1)at the inclusion date

analogue scale between 0 to 10 at the last follow-up (0 equal minimum; 10 equal maximum)

Trial Locations

Locations (1)

CHUR de Brest

🇫🇷

Brest, France

© Copyright 2025. All Rights Reserved by MedPath