A single-center, prospective, open-label, randomized, comparative, and placebocontrolled observation study for effect of using Mobile App-based Human Coaching Program on NAFLD
- Conditions
- Diseases of the digestive system
Recruitment & Eligibility
- Status
- Active, not recruiting
- Sex
- All
- Target Recruitment
- 100
1. Male or female aged 19 years or older and under 65 years of age at the time of writing the written consent
2. Patients diagnosed with NAFLD (non-alcoholic fatty liver disease) as a result of ultrasound examination
3. Patients diagnosed with fatty liver (CAP value >238 dB/m) by transient elastography
4. Those who voluntarily consented in writing to the research
1. Patients who meet the criteria for alcoholic fatty liver disease (in case of exceeding 210 g per week for men and 140 g per week for women for the past 2 years)
2. Patients with liver disease other than fatty liver
3. Cirrhosis patients with reduced liver function (CTP class B and C)
4. Those taking drugs that can cause fatty liver (thiazolidinedione, SGLT2i class, amiodarone, methotrexate, tamoxifen, valproate, corticosteroids, etc.)
5. Patients treated with oral or parenteral corticosteroids chronically (>14 consecutive days) within 8 weeks prior to screening
6. Patients with malnutrition, starvation, debilitating conditions (including patients with severe infections and severe trauma before and after surgery), pituitary insufficiency or adrenal insufficiency
7. Patients receiving or receiving radiation and chemotherapy for malignant tumors for less than 2 years
8. Patients undergoing gastrointestinal bypass
9. Heart failure (class III-IV in NYHA classification) or uncontrolled arrhythmias within 6 months
10. Those with acute cardiovascular disease within 12 weeks
(Patients with a history of unstable angina, myocardial infarction, transient ischemic attack, cerebrovascular disease, coronary artery bypass graft, or coronary intervention)
11. Patients with renal failure, chronic renal disease (estimated glomerular filtration rate <60 mL/min/1.73 m2) or patients on dialysis
12. Anemic patients with an Hb level of less than 10.5 g/dL
13. Others who are unable to participate in the research due to the judgment of the researcher
14. Persons unable to read consent forms (eg illiterate, foreigners, etc.)
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method