Magnetic versus standard technique for sentinel node biopsy in breast cancer

Not Applicable

Completed

• Conditions: Breast cancer; Malignant neoplasm of breast; Cancer

• Registration Number: ISRCTN20200149
• Lead Sponsor: Guy's and St Thomas' NHS Foundation Trust

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-12-15
• Study Completion: 2020-01-01
• Last Update Posted: 19 April 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 924

Inclusion Criteria

Patients with breast cancer scheduled for SLNB and who are clinically and radiologically node negative

Exclusion Criteria

1. Known intolerance/hypersensitivity to iron or dextran compounds
2. Patients who decline to receive radioisotope for SLNB
3. Patients with a pacemaker or other implantable devices in the chest wall

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<br> 1. Overall SLNB identification rate (proportion of successful SLNBs) with either the standard or the new technique<br> 2. SLNB identification rate within the cohort of patients with involved nodes<br>

Secondary Outcome Measures

Name	Time	Method
<br> 1. Morbidity from SLNB (including staining and lymphoedema rate)<br> 2. Locoregional recurrence<br> 3. Cost effectiveness (health economics)<br> 4. Patient-reported outcome measures (PROMS) with both techniques<br>