Quality of Life in Patients With Permanent Hypoparathyroidism After Total Thyroidectomy in a Swedish Population Based Cohort
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 1,700
- 试验地点
- 1
- 主要终点
- Quality of Life using SF-36 short form
研究概览
简要总结
Quality of life study. The study with include all patients operated with total thyroidectomy between 2005-2015 in Uppsala-Örebro healthcare region, Sweden. The study population has been identified in a previous study and includes close to 1700 patients, of which about 200 developed permanent hypoparathyroidism after surgery.
Quality of Life will be assessed using SF-36 Health Surgery and the outcome for patients with and without permanent hypoparathyroidism will be compared.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Total thyroidectomy between 2005-2015 in Uppsala-Orebro healthcare region.
排除标准
- •Malignancy
- •Sternotomy
- •Previous thyroid surgery
- •Previous or concurrent parathyroidectomy
结局指标
主要结局
Quality of Life using SF-36 short form
时间窗: 2021
The SF-36 yields eight scale scores and two summary scores, the physical component summary (PCS) and mental component summary (MCS). Scoring PCS and MCS involves three steps: 1) standardization of the scales (z-scores) 2) aggregation of score scales and 3) transformation of summary scores (t-scores). For each domain (PCS and MCS) the mean score is 50 with a standard deviation of 10. Higher scores indicates better quality of life (score range 0-100)
次要结局
未报告次要终点