NL-OMON32256尚未招募2 期
Prazosin for the treatment of Obsessive Compulsive Disorder: An open label, fixed dose add-on study. - Prazosin for therapy resistant OCD.
适应症
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 入组人数
- 15
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •DSM IV diagnosis obsessive-compulsive disorder
- •Y-BOCS score > 16
- •Therapy resistance (no response to at least 1 previous SRI treatment)
- •Male and female, aged 18-70 years
- •negative pregnancy test
- •Written informed consent
排除标准
- •Presence of major depression (HDRS>15), bipolar disorder, schizophrenia or any other psychotic condition, tic disorder, substance related disorder during the past 6 months, epilepsy, or any structural CNS disorder or stroke within the last year.
- •Evidence of clinically significant and unstable somatic abnormalities.
- •Patients at risk for suicide
- •Multiple serious drug allergies or known allergy for the trial compounds
- •Use of antipsychotics during 6 months before the screening visit
- •Use of any other psychotropic drug during 6 months before the screening visit
- •Cognitive and behavioural treatment 3 months prior to the screening visit
- •Use of drugs that interact with prazosin: diuretic, other antihypertensive agents, regular use of alcohol.
研究者
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