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Clinical Trials/NCT00623298
NCT00623298
Terminated
Phase 2

Narrative Exposure Therapy Versus Group Interpersonal Psychotherapy -A Controlled Clinical Trial With Orphaned Survivors of the Rwandan Genocide

University of Konstanz0 sites26 target enrollmentJanuary 2005

Overview

Phase
Phase 2
Intervention
Not specified
Conditions
Posttraumatic Stress Disorder
Sponsor
University of Konstanz
Enrollment
26
Primary Endpoint
Symptoms of posttraumatic stress disorder, symptoms of depression
Status
Terminated
Last Updated
18 years ago

Overview

Brief Summary

The present study is a pragmatic trial that investigates the efficacy and usefulness of two treatment modules in a sample of Rwandan genocide orphans: Narrative Exposure Therapy (NET) versus group-Interpersonal Psychotherapy (IPT). We used a half year baseline to measure the treatment-induced changes. We hypothesized that there would be a greater reduction in posttraumatic stress symptoms in the NET- than in the IPT-group and that IPT would be superior to NET in the reduction of depression symptoms.

Detailed Description

The 1994 genocide of Rwanda has left countless children orphaned. 26 Rwandan orphans who fulfilled DSM-IV diagnosis of PTSD were offered participation in a controlled treatment trial. A group adaptation of Interpersonal Psychotherapy (IPT, n = 14) was compared to Narrative Exposure Therapy (NET, n = 12). Main outcome measures were symptoms of PTSD and depression assessed pre-treatment, 3 months after therapy (post-test) and 6 months after therapy (follow-up) using the CAPS, MINI and Hamilton Rating Scale. At post-test, participants in both treatment conditions showed reductions in posttraumatic stress symptoms and depression symptoms. At 6-month follow-up, NET proved to be more effective in the treatment of PTSD. Only 25% (n = 3) of NET-participants but 71% (n = 10) of the IPT-participants still fulfilled PTSD criteria at follow-up. Although there was a significant reduction in depression symptoms in both treatment groups from pre-test to follow-up, NET again proved to be more effective. This treatment-trial demonstrates that NET and group-IPT are suitable treatment modules even when most severe traumatic stress and difficult living conditions have led to chronic mental suffering.

Registry
clinicaltrials.gov
Start Date
January 2005
End Date
March 2006
Last Updated
18 years ago
Study Type
Interventional
Sex
All

Investigators

Sponsor
University of Konstanz

Eligibility Criteria

Inclusion Criteria

  • Rwandan orphans who have experienced the genocide, who lost at least one parent during the genocide and who were no older than 18 years during the genocide

Exclusion Criteria

  • Mental retardation
  • Psychotic symptoms or current drug or alcohol

Outcomes

Primary Outcomes

Symptoms of posttraumatic stress disorder, symptoms of depression

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