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Clinical Trials/NCT06432218
NCT06432218
Not Yet Recruiting
N/A

A Randomized Controlled Trial of the Effectiveness of Patient Education in the Clinical Management of Pessary

Peking Union Medical College Hospital1 site in 1 country280 target enrollmentJune 2024

Overview

Phase
N/A
Intervention
Not specified
Conditions
Pelvic Organ Prolapse
Sponsor
Peking Union Medical College Hospital
Enrollment
280
Locations
1
Primary Endpoint
Continued usage with satisfaction
Status
Not Yet Recruiting
Last Updated
last year

Overview

Brief Summary

This study is a prospective, randomized, controlled, single-blinded, multi-center clinical trial. Symptomatic patients with pelvic organ prolapse (POP) stage II, III or IV arranged to undergo pessary treatment will be randomized into either the experimental group or the control group. All patients will receive conventional verbal/paper instruction and counseling from a specialized doctor or nurse before pessary fitting, and the experimental group will receive additional patient education in the form of a re-watchable video. The video mainly includes a short introduction of pessary treatment for pelvic organ prolapse, tips and tricks for wearing and self-management of pessary, possible adverse reactions and remedy. All patients will receive regular pessary fitting and be followed up for 1 year. Self-assessment questionnaires will be used to assess the patients' willingness to pessary treatment, anxiety status, treatment satisfaction and efficacy, and to assess the patients' self-management, complications and treatment adherence. Then the differences between the two groups will be compared.

Registry
clinicaltrials.gov
Start Date
June 2024
End Date
November 2026
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Symptomatic pelvic organ prolapse of stage II\~IV
  • Ability to participate in clinical trial and follow-up
  • The patient and family understand the study, are willing to participate in the 1-year study, and provide written informed consent

Exclusion Criteria

  • Acute phase of infection of the internal and/or external genital tracts
  • Genital fistula
  • Suspected or untreated lower genital tract tumors
  • Abnormally elevated intra-abdominal pressure (e.g., ascites, tumors)
  • Life expectancy less than 1 year
  • Cognitive or language communication disorders
  • Unable to watch video (e.g., blindness)

Outcomes

Primary Outcomes

Continued usage with satisfaction

Time Frame: 12 months after pessary fitting.

Continued usage of the pessary and have very much or much improvement in the patient impression of improvement (PGI-I) questionnaire at 1 year.

Secondary Outcomes

  • Willingness to treatment(Baseline, at pessary fitting, and 3 and 12 months after successful pessary fitting.)
  • Anxiety about pessary use(Baseline and at pessary fitting.)
  • Improvement in symptoms(3 and 12 months after successful pessary fitting.)
  • Treatment-related symptoms and complications(3 and 12 months after successful pessary fitting.)
  • Knowledge of pessary(Baseline and at pessary fitting.)
  • Ability to self-manage(3 and 12 months after successful pessary fitting.)
  • Improvement in quality of life(3 and 12 months after successful pessary fitting.)
  • Improvement in sexual activity(3 and 12 months after successful pessary fitting.)

Study Sites (1)

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