Sambucus ebulus effect on knee Osteoarthritis
Phase 3
- Conditions
- knee osteoartritis.Primary arthrosis of other joints
- Registration Number
- IRCT2014080318494N1
- Lead Sponsor
- Vice Chancellor for research, Shahid Sadoughei University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 94
Inclusion Criteria
Inclusion Criteria: age: 30-60 years; A history of knee pain for at least 3 months; Mild to moderate Osteoarthritis (grade 1 and 2) based on Kellegren-Lawrence grading scale;
Exclusion Criteria
1-Allergy to Sambucus ebulus & Diclofenac gel; Skin lesions in the knee; Osteoarthritis secondary to Rheumatic disease such as Rheumatoid Arthritis, Gout, Infectious Arthritis, Metabolic Arthritis, Traumatic Arthritis; Knee joint replacement surgery; Oral and topical steroid therapy within 14 days prior to study; Intra-articular steroid injections within 90 days prior to study; Pregnancy and Lactation; Addiction to alcohol and drugs; Radiculopathy and Neuropathy
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pain. Timepoint: Baseline, 2 and 4 weeks after intervention. Method of measurement: WOMAC questionnaire.;Stiffness. Timepoint: Baseline, 2 and 4 weeks after intervention. Method of measurement: WOMAC questionnaire.
- Secondary Outcome Measures
Name Time Method Physical function. Timepoint: Baseline, 2 and 4 weeks after intervention. Method of measurement: WOMAC questionnaire.