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Phase I study of combination chemotherapy with nab-paclitaxel and Nedaplatin as first-line treatment in patients with advanced squamous cell lung cancer.

Phase 1
Conditions
Squamous cell lung cancer
Registration Number
JPRN-UMIN000010963
Lead Sponsor
Kitasato University School of Medicine Department of Respiratory Medicine
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
All
Target Recruitment
16
Inclusion Criteria

Not provided

Exclusion Criteria

1) Severe infection. 2) Severe complications. 3) Uncontrollable pleural or pericardial effusion or ascites. 4) Superior vena cava syndrome. 5) Simultaneous or metachronous double cancers. 6) Symptomatic brain metastases. 7) Prior radiotherapy for primary tumor. 8) Radiotherapy other than primary tumor within 2 weeks. 9) A history of serious drug allergy or severe allergic reaction with albumin. 10) Psycologic illness

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Finding a decomending dose
Secondary Outcome Measures
NameTimeMethod
evaluation of safety and response rate
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