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Clinical Trials/ACTRN12614000583640
ACTRN12614000583640
Completed
未知

Pregnant women with a normal BMI receiving dietary, lifestyle and exercise advice compared with routine antenatal care to improve maternal and infant health outcomes.

Discipline of Obstetrics and Gynaecology, Faculty of Health Sciences, The University of Adelaide0 sites641 target enrollmentMay 30, 2014

Overview

Phase
未知
Intervention
Not specified
Conditions
Not specified
Sponsor
Discipline of Obstetrics and Gynaecology, Faculty of Health Sciences, The University of Adelaide
Enrollment
641
Status
Completed
Last Updated
6 years ago

Overview

Brief Summary

There are well-recognised associations between excessive gestational weight gain (GWG) and adverse pregnancy outcomes, including an increased risk of high blood pressure in pregnancy, gestational diabetes, and caesarean birth. The aim of the OPTIMISE randomised trial was to evaluate the effect of dietary and exercise advice among pregnant women who were considered to be in the healthy weight range, on pregnancy and birth outcomes. The trial was conducted in Adelaide, South Australia. Pregnant women with a body mass index in the healthy weight range (18.5 – 24.9 kg/m2) were enrolled in a randomised controlled trial of a dietary and lifestyle intervention versus standard antenatal care. The dietitian-led dietary and lifestyle intervention over the course of pregnancy, and was based on the Australian Guide to Healthy Eating. When we looked at the results we found that the two study groups, dietary and lifestyle intervention group and standard care group, were of similar age, starting weight, ethnicity and number of previous pregnancies. We found that women in the intervention group improved their diet, and pregnancy and birth outcomes were similar between the two groups including infant birthweight above 4 kg, a risk factor for childhood obesity. Women in both groups gained a similar amount of weight during pregnancy.

Registry
who.int
Start Date
May 30, 2014
End Date
December 15, 2018
Last Updated
6 years ago
Study Type
Interventional
Sex
Female

Investigators

Sponsor
Discipline of Obstetrics and Gynaecology, Faculty of Health Sciences, The University of Adelaide

Eligibility Criteria

Inclusion Criteria

  • Women with a singleton, live gestation between 10\+0\-20\+0 weeks who are of normal BMI (defined as a BMI 18\.5\-24\.9kg/m2\), at the time of the first antenatal visit.

Exclusion Criteria

  • Women with a multiple pregnancy; type 1 or 2 diabetes diagnosed prior to pregnancy; or a BMI of 25\.0kg/m2 or more will be excluded.

Outcomes

Primary Outcomes

Not specified

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