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临床试验/ACTRN12614000583640
ACTRN12614000583640已完成未知

Pregnant women with a normal BMI receiving dietary, lifestyle and exercise advice compared with routine antenatal care to improve maternal and infant health outcomes.

Discipline of Obstetrics and Gynaecology, Faculty of Health Sciences, The University of Adelaide0 个研究点目标入组 641 人开始时间: 2014年5月30日最近更新:

试验速览

阶段
未知
状态
已完成
发起方
入组人数
641

研究概览

简要总结

There are well-recognised associations between excessive gestational weight gain (GWG) and adverse pregnancy outcomes, including an increased risk of high blood pressure in pregnancy, gestational diabetes, and caesarean birth. The aim of the OPTIMISE randomised trial was to evaluate the effect of dietary and exercise advice among pregnant women who were considered to be in the healthy weight range, on pregnancy and birth outcomes. The trial was conducted in Adelaide, South Australia. Pregnant women with a body mass index in the healthy weight range (18.5 – 24.9 kg/m2) were enrolled in a randomised controlled trial of a dietary and lifestyle intervention versus standard antenatal care. The dietitian-led dietary and lifestyle intervention over the course of pregnancy, and was based on the Australian Guide to Healthy Eating. When we looked at the results we found that the two study groups, dietary and lifestyle intervention group and standard care group, were of similar age, starting weight, ethnicity and number of previous pregnancies. We found that women in the intervention group improved their diet, and pregnancy and birth outcomes were similar between the two groups including infant birthweight above 4 kg, a risk factor for childhood obesity. Women in both groups gained a similar amount of weight during pregnancy.

研究设计

研究类型
Interventional
分配方式
Randomised controlled trial
主要目的
Prevention
盲法
Open (masking not used)

入排标准

年龄范围
16 Years 至 50 Years(—)
性别
Female

入选标准

  • Women with a singleton, live gestation between 10+0-20+0 weeks who are of normal BMI (defined as a BMI 18.5-24.9kg/m2), at the time of the first antenatal visit.

排除标准

  • Women with a multiple pregnancy; type 1 or 2 diabetes diagnosed prior to pregnancy; or a BMI of 25.0kg/m2 or more will be excluded.

研究者

发起方
Discipline of Obstetrics and Gynaecology, Faculty of Health Sciences, The University of Adelaide

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