The effectiveness and safety of a Picosecond laser 1064-nm for treatment of lip hyperpigmentation in Thai populatio
- Conditions
- lip hyperpigmentationLip
- Registration Number
- TCTR20231005005
- Lead Sponsor
- Institute of Dermatology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Enrolling by invitation
- Sex
- All
- Target Recruitment
- 41
1. Lip hyperpigmentation characterized by bilateral hyperpigmented patch on upper and/or lower lip
1. Lip hyperpigmentation from disease such as lichen planus, lupus erythematosus, pemphigus, pemphigoid, fixed drug eruptions, pigmented contact cheilitis, orofacial granulomatosis, ephelides, labial melanotic macule, acquired dermal melanocytosis, melanoacanthoma, lentigines, nevus, malignant melanoma, pigmented Bowen disease, squamous cell carcinoma, melanoma, actinic cheilitis, Lentiginosis syndromes, Addison disease, Cushing disease, Nelson syndrome, acromegaly, hyperthyroidism, and hemochromatosis which diagnose by history taking and physical examination
2. History of procedures at lip such as tattoo, filler injection or laser
3. History of keloid or hypertrophic scar
4. History of labial herpes infection
5. Infection at lip
6. Pregnancy or breast feeding
7. History of smoking
8. History of drugs such as minocycline, zidovudine, cyclophosphamide, doxorubicin, escitalopram, levodopa, nicotine and tacrolimus
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Melanin index at 6 months after end of the laser Mexameter
- Secondary Outcome Measures
Name Time Method Physician assessment at 6 months after end of the laser Physician assess percentages of improvement of lip hyperpigmentation,Patient satisfaction at 6 months after end of the laser Patient reported outcome using a customer satisfaction scores