A study of platelet rich plasma in laparoscopic cholecystectomy in prevention of infection and better cosmetic outcome
Not Applicable
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2023/05/052875
- Lead Sponsor
- Department of General Surgery institute of medical sciences Banaras Hindu university
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Patients of Symptomatic gallstones disease
2. Age 25-45 years
3. ASA grade l/ll
4. Ready to give consent for participation
Exclusion Criteria
1. Comorbid conditions [Diabetes mellitus/HIV/immune compromised]
2. Platelet counts <150000/ Disorder of platelet function
3. Systemic infection/ Fever within 4 weeks prior to surgery
4. Conversion to open cholecystectomy
5. Intraoperative complications requiring prolonged hospital stay
6. Any suspicious of malignancy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. To evaluate the incidence of port site infection using Southampton scoring system following laparoscopic cholecystectomy using port site platelet rich plasma infiltration in comparison to placeboTimepoint: Post operative day (POD) 1 <br/ ><br>POD 2 <br/ ><br>POD 10 <br/ ><br>1 month <br/ ><br>3 month
- Secondary Outcome Measures
Name Time Method 1. Evaluation of the incidence of post-operative pain using numerical rating scale (NRS) and assessment of wound healing progress by redness, oedema, ecchymosis, discharge and approximation (REEDA) scale and Vancouver scar scale (VSS) following laparoscopic cholecystectomy using port site platelet rich plasma infiltration in comparison to placeboTimepoint: Post operative day (POD) 1 <br/ ><br>POD 2 <br/ ><br>POD 10 <br/ ><br>1 month <br/ ><br>3 month