Efficacy of Clinacanthus nutans Lindau cream comparing with podophyllin for treating anogenital warts among Thai males: A self-comparison, randomized controlled trial

Phase 1

Recruiting

• Conditions: anogenital wart; podophyllin; clinacanthus nutans lindau cream

• Registration Number: TCTR20170621003
• Lead Sponsor: Siriraj hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2017-06-21
• Study Completion: 2017-12-31
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Male
• Target Recruitment: 12

Inclusion Criteria

1. male patients 18 years and older
2. diagnosed as anogenitalwart
3. at least two lesions of wart which are at least 1 cm apart
4. consent form obtained

Exclusion Criteria

1. patients with HIV infection
2. patients on immunosuppressive drugs
3. patients with autoimmune disease

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
size reduction of anogenital wart 4 week quantitative measurement(mm)

Secondary Outcome Measures

Name	Time	Method
viral loads of genital wart 4 week quantitative measurement(digital droplet PCR- Each droplet represents as 1 HPV DNA copy),gene expression of genital wart 4 week qualitative measurement(Nanostring technology- number of gene for log fold change compare to houseke,side effects of clinacanthus nutans lindau cream 4 week qualitative measurement(clinical symptoms- erythema, ulceration)