Randomized controlled clinical trial on the intervention of activating blood circulation and removing toxicity Chinese herbal compound in patients with borderline coronary lesions
- Conditions
- coronary heart disease
Recruitment & Eligibility
- Status
- Pending
- Sex
- Male
- Target Recruitment
- Not specified
(1)Patients with coronary artery bordeline lesions confirmed by coronary angiography or coronary computed tomographic angiography with stenosis of at least one major coronary artery lumen between 50% and 70%;
(2) Patients aged 18–80 years.
(3) Patients with heart function grading of NYHA grade?-?
(4) Patients conform to the TCM standard of blood stasis syndrome
(5) Patients will be informed about the trial and should voluntarily sign the consent form.
(1) Patients who had previously undergone coronary stent implantation, coronary artery bypass grafting or acute myocardial infarction within 3 months;
(2) Patients with diffuse lesions throughout the diseased vessels;
(3) Those who had previously undergone other cardiac operations, such as valve replacement;
(4) Patients with severe heart, liver and renal insufficiency, who are not suitable for coronary angiography and related examination and treatment;
(5) Persons suffering from mental disorders;
(6) Persons suffering from hepatitis, tuberculosis, AIDS and other infectious diseases;
(7) Allergic constitution;
(8) Pregnant and lactating women;
(9) Those whose life expectancy is less than one year;
(10) Participated in other clinical researchers within the last 3 months.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Coronary artery calcification score;Gensini score of coronary arteri;MACE;
- Secondary Outcome Measures
Name Time Method MMP-9;hs-CRP;