跳至主要内容
临床试验/NCT04304885
NCT04304885Unknown不适用

Effect of Sonication on Periprosthetic Joint Infection Treatment Strategy.

Bezmialem Vakif University1 个研究点 分布在 1 个国家目标入组 56 人开始时间: 2020年3月15日最近更新:
适应症

试验速览

阶段
不适用
入组人数
56
试验地点
1
主要终点
Sensitivity

研究概览

简要总结

It is not known in the literature how much sonication affects the patient's treatment. Another important issue is that the place of this method in diagnosis is not clear. The aim of this study is to contribute to the literature on this issue and to determine the sensitivity and specificity of sonication prospectively using the new definition and effect of sonication on the treatment strategy in terms of infection in patients with PJI.

详细描述

Total knee and hip arthroplasties are successful surgical procedures that are widely applied all over the world and provide high patient satisfaction and increased quality of life. Periprosthetic joint infection (PJI), is a serious complication that negatively affects the targeted result, decreases patient satisfaction, and increases morbidity and mortality after total joint replacement. Another important issue, the previous infection is the most important reason for the failure of surgery in revision arthroplasty. It is known that the success of PJI treatment seriously can be affected by the type of microorganism and antibiotic sensitivity. Therefore, microbiological examination methods are always of interest, and one of them is the sonication method.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

性别
All
接受健康志愿者

入选标准

  • All patients scheduled for revision arthroplasty (aseptic revision, septic revision, instability, and periprosthetic fracture)

排除标准

  • who do not accept to participate in research
  • insufficient data for new definition criteria
  • acute periprosthetic infections
  • patients with systemic inflammatory disease

结局指标

主要结局

Sensitivity

时间窗: 14 days

To determine how many patients diagnosed with periprosthetic joint infection can be detected by sonication method.

次要结局

  • The change in antibiotic treatment.(14 days)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Orkhan Aliyev

Residents Doctor in Orthopedics Department

Bezmialem Vakif University

研究点 (1)

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