CTRI/2024/07/070076尚未招募2/3 期
Comparison of Nebulized Ketamine-Lignocaine versus Nalbuphine-Lignocaine inhalation on intubating conditions and hemodynamic responses during Awake Fiberoptic Intubation
试验速览
- 阶段
- 2/3 期
- 状态
- 尚未招募
- 入组人数
- 64
- 试验地点
- 1
- 主要终点
- To Compare the facial grimace scores, cough scores, sedation score between the groups
研究概览
简要总结
This study is a randomized, double blind trial comparing compare the efficacy of ketamine and nalbuphine with lignocaine in blunting the hemodynamic response during Awake Fibreoptic Intubation that is being conducted at AIIMS Raebareli. The primary outcome is to compare the facial grimace scores, cough scores and sedation score between the groups as well as tp compare the hemodynamic parameters among the two groups.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant, Investigator, Outcome Assessor and Date-entry Operator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •American society of anaesthesiology grade I and II
- •Patients suspected to have difficult intubation requiring fibreoptic as an aid.
排除标准
- •1.Pregnancy 2.Coagulopathy (Bleeding airway) 3.Cerebrovascular disease 4.systemic infection 5.Inability to understand the study protocol 6.Allergy to either of the drugs ketamine/nalbuphine/lignocaine 7.Psychopathy that may affect patient evaluation 8.Patient refusal 9.Pateints with significant renal, hepatic, pulmonary and neurological diseases 10.Pateints with history of drug abuse.
结局指标
主要结局
To Compare the facial grimace scores, cough scores, sedation score between the groups
时间窗: 24hrs
To compare the hemodynamic parameters among the two groups
时间窗: 24hrs
次要结局
- To Compare Time taken for AFOI and Patient satisfaction scores in both the groups(12 hours)
研究者
Dr. Mukesh sirvi
All India Institute of Medical Sciences
研究点 (1)
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