Effect of neuromuscular blockade reversal agent on BIS (bispectral index) and EMG (electromyelogram) under desflurane anesthesia. A double-blind, randomized control trial

Not Applicable

Completed

Conditions: Diseases of the digestive system

Registration Number: KCT0002762

Lead Sponsor: Samsung Medical Center

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: All

Target Recruitment: 66

Inclusion Criteria

Among the patients scheduled for surgery

1) American society of anesthesiologist physical status (ASA PS) I-III adult patients (aged 19-65)
2) Patients scheduled for laparoscopic cholecystectomy using desflurane

Exclusion Criteria

1) Children (18 years old or younger)
2) BMI> 25 kg / m 2 or <18.5 kg / m 2
3) Neuromuscular disease or mental illness
4) Those diagnosed with metabolic diseases
5) Drug addiction or alcohol addiction
6) Liver, kidney disease
7) Pregnant and lactating women
8) Emergency surgery
9) Those who fall under the taboo disease of each drug
- Patients with glaucoma, obstructive uropathy, patients with obstructive gastrointestinal disease, patients with paralytic ileus, patients with severe ulcerative colitis, patients with giant colic,

Study & Design

Study Type: Interventional Study

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
We will compare the BIS before the administration of neostigmine, pyridostigmine, and sugammadex (N, P, S) and after regain TOF ratio 0.9 in three groups while maintaining inhalation anesthetics.

Secondary Outcome Measures

Name	Time	Method
The difference in time taken to increase BIS with increasing TOF ratio after each muscle relaxant (N, P, S) administration will be assessed;The difference in the time to increase EMG activity with increasing TOF ratio after each muscle relaxant (N, P, S) administration will be evaluated.