Vitality Oriented Innovation for the Lifecourse of the Ageing Society - Intervention Study - VOILA

eids Universitair Medisch Centrum0 个研究点目标入组 220 人开始时间: 待定最近更新: 2024年8月19日

适应症

试验速览

暂无简介。

•All participants: age 60 or older, body mass index 18.5-35.0 kg/m2,
•community-dwelling, mentally competent (MMSE score 24 or over). Depending on
•the group the main additional criteria are: 1) metabolically compromised group:
•Metabolomic Mortality Score within the top half of the batch of subjects 60
•years and older from and also outside the LLS cohort 2) mobility compromised
•group: using a walking aid and/or slow 5-times chair stand test (>15 seconds)
•3) total knee replacement groups (intervention group and control group): living
•in/or around the areas of Maastricht, Eindhoven, and Venlo/Roermond/Nijmegen
•and underwent elective total knee replacement surgery ~6 weeks before start of
•study 4) healthy active reference group: meeting the Dutch norms for being
•physically active, Metabolic Mortality Score below the top half of of the batch
•of subjects 60 years and older from and also outside the LLS cohort

•Already using prebiotic fibres or high doses of supplements, contraindications
•for using milk/lactose/calcium/vitamin D, engagement in intense physical
•activity, (aforementioned criteria are not exclusion criteria for the reference
•group), eGFR <30 ml/min/1.73 m2, diseases, conditions or disorders which may
•affect the ability to follow the study protocol and which cannot be overcome
•with help of a caregiver, current participation in other scientific research
•that conflicts with this study, Not signed up to a general practitioner, No
•permission to request information from the general practitioner/ treating
•specialist(s) about medical history, medication use

发起方