Treatment of Exertional Heatstroke witH icE wAter Soaked Towels
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 55
- 试验地点
- 1
- 主要终点
- cooling rate
研究概览
简要总结
Exertional heat stroke (EHS) is the most serious form of heat-illness that can occur during sports and exercise. If not recognized and treated immediately mortality rate of EHS is high. Early recognition and initiation of cooling are paramount. If temperature is reduced to < 40°C within 30 minutes of symptom onset, most patients recover completely. There are several strategies for cooling in EHS, including cooling with rotating in ice water soaked towels which cover the body of a patient.
The aim of this research is to investigate the effectiveness and safety of treatment of EHS with ice water soaked towels to lower body temperature.
详细描述
Rationale: Exertional heat stroke (EHS) is the most serious form of heat-illness that can occur during sports and exercise. If not recognized and treated immediately mortality rate of EHS is high. Early recognition and initiation of cooling are paramount. If temperature is reduced to < 40°C within 30 minutes of symptom onset, most patients recover without sequelae. Exertional heat exhaustion (EHE) is a precursor of EHS, and might develop in EHS if exercise is not terminated. There are several strategies for cooling in EHS, including cooling with rotating in ice water soaked towels which cover the body of a patient.
Objective: The aim of this research is to investigate the effectiveness and safety of treatment of EHS with ice water soaked towels to lower body temperature. Secondary objectives include cooling rate of ice water soaked towels, morbidity of EHS and HE, productivity loss related to EHS and EHE and the development of posttraumatic stress symptoms and PTSD after treatment for EHS and EHE.
Study design: We will conduct a prospective longitudinal observational study. Patients will be monitored and treated according the national guideline in the medical facility. A follow-up survey will be performed after two weeks and two months.
Study population: All participants of 18 years and older who received medical care for EHS or EHE at the City Pier City race on March 12th 2023 and Rotterdam Marathon on April 16th 2023.
Main study parameters/endpoints: Primary outcome will be the cooling rate of treatment with rotating in ice water soaked towels. Secondary outcomes will be percentage of patients with EHS that were cooled to a temperature lower than 40°C within 30 minutes after entering a medical facility (or collapse).
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •In order to be eligible to participate in this study, a subject must meet all of the following criteria:
- •≥18 years
- •Receive medical care at in the medical facility the City Pier City and Marathon Rotterdam 2023
- •Tympanic temperature >38.0°C
排除标准
- •A potential subject who meets any of the following criteria will be excluded from participation in this study:
- •Language barrier (not proficient in Dutch or English)
结局指标
主要结局
cooling rate
时间窗: during treatment in medical facility up to 2 hours after entering the facility
cooling rate of treatment with rotating in ice water soaked towels
次要结局
- productivity loss (abscens of work) related to EHS and EHE(2 months after EHS/EHE)
- Morbidity of EHS/EHE(2 weeks and 2 months after EHS/EHE)
- Posttraumatic stress symptoms after EHS and EHE(6 months after EHS/EHE)
- percentage cooled to a temperature <40°C within 30 minutes(30 minutes after entering medical facility)
研究者
Amber Hoek
Principal Investigator, Emergency Physician, MD, PhD
Erasmus Medical Center