Aloe Vera in Irritable Bowel Syndrome
- Conditions
- Irritable Bowel Syndrome
- Interventions
- Dietary Supplement: Placebo controlDietary Supplement: Aloe vera effervescent tablet (AVH200)
- Registration Number
- NCT01400048
- Lead Sponsor
- Sahlgrenska University Hospital, Sweden
- Brief Summary
The purpose of the present study is to study the effect of aloe vera in the treatment of IBS patients in a randomized, double-blind placebo controlled study.
- Detailed Description
There is limited knowledge of the IBS pathophysiology, absence of biological markers and therefore few effective treatment options. IBS therefore contributes to difficulties in the management of the patients. Aloe vera has a long association with herbal medicine, from the Ebers Papyrus from 16th century BCE. It is alleged to be effective in treatment of wounds, to improve blood glucose levels in diabetics, and it may reduce symptoms and inflammation in patients with ulcerative colitis. Evidence of the effects of aloe vera in the treatment of IBS, is however limited and contradictory.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 173
- IBS according to the Rome III criteria
- Adults
- other GI disorders
- other medical conditions
- were pregnancy or breast-feeding
- food allergy or intolerance to other than lactose
- ongoing intake of aloe vera products
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Placebo Placebo control - Aloe vera effervescent tablet (AVH200) Aloe vera effervescent tablet (AVH200) -
- Primary Outcome Measures
Name Time Method IBS symptoms 4 weeks
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Mag-tarmlab, Dept of Internal Medicine, Sahlgrenska University Hospital
🇸🇪Gothenburg, Sweden