Aloe Vera Versus Placebo for Patients With Irritable Bowel Syndrome
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 173
- 试验地点
- 2
- 主要终点
- IBS symptoms
研究概览
简要总结
The purpose of the present study is to study the effect of aloe vera in the treatment of IBS patients in a randomized, double-blind placebo controlled study.
详细描述
There is limited knowledge of the IBS pathophysiology, absence of biological markers and therefore few effective treatment options. IBS therefore contributes to difficulties in the management of the patients. Aloe vera has a long association with herbal medicine, from the Ebers Papyrus from 16th century BCE. It is alleged to be effective in treatment of wounds, to improve blood glucose levels in diabetics, and it may reduce symptoms and inflammation in patients with ulcerative colitis. Evidence of the effects of aloe vera in the treatment of IBS, is however limited and contradictory.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •IBS according to the Rome III criteria
排除标准
- •other GI disorders
- •other medical conditions
- •were pregnancy or breast-feeding
- •food allergy or intolerance to other than lactose
- •ongoing intake of aloe vera products
研究组 & 干预措施
Aloe vera effervescent tablet (AVH200)
干预措施: Aloe vera effervescent tablet (AVH200) (Dietary Supplement)
Placebo
干预措施: Placebo control (Dietary Supplement)
结局指标
主要结局
IBS symptoms
时间窗: 4 weeks
次要结局
未报告次要终点
研究者
Magnus Simrén
Professor
Sahlgrenska University Hospital, Sweden