Study on the Protective Effect of Gastrodin on Myocardial Injury in Patients Undergoing Cardiac Surgery
Recruiting
- Conditions
- Cardiac Surgical Procedures
- Registration Number
- NCT06012968
- Lead Sponsor
- Wuhan Union Hospital, China
- Brief Summary
This study intends to include hypertrophic cardiomyopathy patients over 18 years old who underwent cardiac surgery in our hospital. Patients were divided into medication group and control group according to the use of gastrodin during operation. The patients ' myocardial tissue samples were collected, the postoperative prognosis data were observed and recorded, and the data were analyzed. The degree of myocardial tissue cell damage and postoperative clinical outcomes were compared between the two groups.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 10
Inclusion Criteria
- Patients with hypertrophic cardiomyopathy aged≥18 years, regardless of gender;
- Patients undergoing elective hypertrophic cardiomyopathy outflow tract surgery;
- Signed informed consent, good compliance.
Exclusion Criteria
- suffering from more serious genetic diseases (such as immunodeficiency, thalassemia, etc.);
- moderate to severe malnutrition, moderate to severe anemia;
- persistent infection;
- severe preoperative underlying diseases (such as severe liver and kidney dysfunction)
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Degree of myocardial cell injury During postoperative hospitalization stay, an average of about two weeks Postoperative myocardial injury marker serum concentration, postoperative cardiac function ultrasound index
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
🇨🇳Wuhan, Hubei, China