Making Memory Better for Seniors With Mild Cognitive Impairment

Not Applicable

Active, not recruiting

• Conditions: Mild Cognitive Impairment

• Registration Number: NCT01532739
• Lead Sponsor: Nova Scotia Health Authority

Brief Summary

The purpose of this study is to investigate the feasibility and effectiveness of a cognitive training group in individuals with Mild Cognitive Impairment, using a new paradigm that will optimize ecological validity by (1) focusing on everyday memory problems, (2) supplementing traditional memory training with the teaching of an empirically-supported problem-solving approach, and (3) employing a clinically representative sample of individuals with MCI (e.g., not excluding those with mild affective symptoms).

Detailed Description

Not available

Study Timeline

• Study Start: 2011-12-05
• Study First Submitted: 2012-02-10
• Study First Submitted QC: 2012-02-10
• Study First Posted: 2012-02-14
• Status Verified: 2024-08
• Last Update Submitted: 2024-08-19
• Last Update Posted: 2024-08-21
• Primary Completion: 2025-12-05
• Study Completion: 2025-12-05

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• Clinical diagnosis of Mild Cognitive Impairment

Exclusion Criteria

• Clinical diagnosis of dementia
• History of neurological conditions known to impair cognition
• History of alcohol or drug abuse
• History of chronic psychiatric illness
• Current symptoms of moderate to severe depression (Geriatric Depression Scale >19) or anxiety (Beck Anxiety Inventory >15)

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Primary Outcome Measures

Name	Time	Method
Change in everyday memory functioning	Measured at baseline and months 3, 5, 8	Rivermead Behavioural Memory Test (3rd Edition)

Secondary Outcome Measures

Name	Time	Method
Change in memory perception	Measured at baseline and months 3, 5, 8	Multifactorial Metamemory Questionnaire
Change on traditional memory testing	Measured at baseline and months 3, 5, 8	California Verbal Learning Test (2nd Edition)
Change in quality of life	Measured at baseline and months 3, 5, 8	Zarit Burden Interview
Change in mood (i.e., self-report symptoms of depression)	Measured at baseline and months 3, 5, 8	Geriatric Depression Scale
Change in mood (i.e., self-report symptoms of anxiety)	Measured at baseline and months 3, 5, 8	Beck Anxiety Inventory
Feasibility	Measured at end of study	Recruitment, retention, and compliance rates
Change in other psychiatric symptoms (informant-report)	Measured at baseline and months 3, 5, 8	Neuropsychiatric Inventory
Change in caregiver burden	Measured at baseline and months 3, 5, 8	Zarit Burden Interview

Trial Locations

Locations (1)

Neuropsychology Service, Nova Scotia Hospital; 🇨🇦 Dartmouth, Nova Scotia, Canada