A study for evaluating the effect of repeated intake of the plant-derived processed food on postprandial fat oxidation.
- Conditions
- othing (healthy subjects)
- Registration Number
- JPRN-UMIN000018843
- Lead Sponsor
- Kao Corporation
- Brief Summary
ineteen healthy subjects participated in this study, and postprandial energy metabolism was evaluated using indirect calorimetry followed by 14-d repeated pre-consumption of TAG (rapeseed oil) as a control or ALA-DAG. As a primary outcome, ALA-DAG induced significantly higher postprandial fat oxidation than TAG. As a secondary outcome, carbohydrate oxidation tended to be decreased. In addition, postprandial energy expenditure was significantly increased by ALA-DAG compared to TAG. These findings suggest that daily ALA-DAG consumption stimulates dietary fat utilization as energy after a meal, as well as greater diet induced thermogenesis in healthy humans. In conclusion, repeated consumption of ALA-DAG enhanced postprandial fat metabolism after a meal, which may partially explain its visceral fat area-reducing effect.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- Male
- Target Recruitment
- 30
Not provided
1. Subjects having a liver, kidney, or heart disease, respiratory disorder, endocrine disorder, metabolic disorder, nervous disorder, consciousness disorder, diabetes, or other diseases. 2. Subjects who have surgical history for disease or injury within the last two months prior to the current study. 3. Subjects who were experienced unpleasant feeling during blood collection or energy expenditure analyzing (metabolic chamber, hood, or mask). 4. Subjects who have donated over 200 mL of blood within the last one month prior to the current study or over 400 mL of blood within the last three months prior to the current study. 5. Subjects who take a medicine for hyperglycaemia, lipidemia, or hypertension. 6. Subjects whose visceral fat area is below 25 cm2. 7. Subjects whose energy expenditure is not stable. 8. Subjects who drink a lot of alcohol. (more than 30 g/day alcohol) 9. Subjects who habitually take the foods for specified health uses (FOSHU), functional food, or dietary supplements (capsules) affecting current study (e.g. fat weight, serum lipid level). (except for subjects who can stop consume them after informed consent) 10. Subjects whose weight change more than 2 kg during past 2 months. 11. Subjects who will plan to go long term business trip or travel (more than 5 days) during current study. 12. Subjects who have allergy against rubber. 13. Subjects who are not used to intake test diet. 14. Subjects who are smoker. 15. Subjects who have possibility for allergic reaction to food. 16. Subjects who can not intake test diet during clinical study period. 17. Subjects who have participated in other clinical study or are planned to participate in other clinical study. 18. Subjects who are judged to be inappropriate for the study based on the access record by medical doctor. 19. Subjects judged as unsuitable for the study by the investigator or medical doctor for other reason.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method