Preemptive Erector Spinae Plane Block Versus Serratus Anterior Plane Block in MRM
- Conditions
- Modified Radical Mastectomy
- Registration Number
- NCT06404918
- Lead Sponsor
- Benha University
- Brief Summary
Modified radical mastectomy (MRM) is one of the most performed surgeries for breast cancer. MRM is associated with significant pain during the immediate postoperative period.
- Detailed Description
Modified radical mastectomy (MRM) is one of the most performed surgeries for breast cancer. MRM is associated with significant pain during the immediate postoperative period.
Inadequate pain management has both psychological and physiological repercussions.
Various local or regional nerve blocks like thoracic epidural, interscalene brachial plexus, paravertebral, pectoral nerve blocks, and erector spinae plane blocks are performed in MRM to provide analgesia.
Ultrasound-guided Erector spinae plane block (USG-ESPB) is one of the novel and effective regional techniques where local anaesthetic is deposited deep into the erector spinae muscle, blocking the ventral and dorsal rami of multiple spinal nerves, and is technically simple, with fewer hemodynamic side effects and with minimal complications
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 70
- female patients
- aged from 18 to 70 years
- with a body mass index ≤ 30 kg/ m2
- American Society of Anesthesiologists (ASA) physical status I-II,
- who were scheduled for MRM for breast cancer
- history of drug allergy,
- psychiatric illness, substance abuse,
- severe cardiovascular or respiratory disease,
- any pre-existing liver disease, metabolic or neurological syndrome, c
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method time of the first rescue analgesic dose 24 hours postoperatively The time when the first dose of rescue analgesia was administered at the recovery room,
- Secondary Outcome Measures
Name Time Method Heart rate changes 15 minutes after performing the block, and then every 30 minutes intraoperatively till the end of surgery, then postoperatively at 1hour and 2 hours, 4hours, 8hours, 12hours, 18hours, 24hours postoperatively. Heart rate (HR) was recorded immediately before induction of anaesthesia, 1
Mean arterial pressure changes 15 minutes after performing the block, and then every 30 minutes intraoperatively till the end of surgery, then postoperatively at 1hour and 2 hours, 4hours, 8hours, 12hours, 18hours, 24hours postoperatively. Mean arterial pressure
Trial Locations
- Locations (1)
Benha University
🇪🇬Banha, Egypt
Benha University🇪🇬Banha, Egypt