Dynamics of Serum Immunologic Markers Levels in During the Delivery and Possible Benefit for Obstetric Emergency Diagnostics

Brno University Hospital1 个研究点分布在 1 个国家目标入组 57 人开始时间: 2018年9月8日最近更新: 2019年9月13日

适应症

试验速览

阶段: 不适用
状态: 已完成
发起方
入组人数: 57
试验地点: 1
主要终点: Change in levels of total C1 inhibitor

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

This study aim to describe dynamics of immunologic markers C1 inhibitor, C3, C4 during the delivery in order to improve early diagnostics of obstetric emergencies, especially with immune etiology.

详细描述

Our prospective observational study will explore the differences between dynamics of the complement components C1 inhibitor, C1 inhibitor activity, C3, C4 during the labour in a group of women with physiologic pregnancy and in a group with a risk of complications (pre-eclampsia, HELLP syndrome, placenta praevia, placental abruption, IUGR, previous post partum hypotony).

We will focus on women undergoing the Caesarean delivery. We will also measure D vitamin levels and ACE levels and search for some contexts.

研究设计

研究类型: Observational
观察模型: Cohort
时间视角: Prospective

入排标准

年龄范围: 15 Years 至 50 Years（Child, Adult）
性别: Female
接受健康志愿者: 否

入选标准

•Pregnant women undergoing the Caesarean delivery
•Signed informed consent

排除标准

•Previous hepatitis or other hepatocyte damage