跳至主要内容
临床试验/CTRI/2025/12/099809
CTRI/2025/12/099809尚未招募不适用

Effects of hybrid-based pulmonary rehabilitation on exercise capacity and quality of life in individuals with post-tubercular sequelae.

KMCH College of Physiotherapy1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2026年1月5日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
40
试验地点
1

研究概览

简要总结

Post tubercular sequelae lead to persistent respiratory symptoms and reduced functional capacity, significantly impacting quality of life. While traditional center-based pulmonary rehabilitation (PR)  has demonstrated benefits in other chronic respiratory conditions-such as COPD, bronchiectasis, cystic fibrosis, asthma with improvements in symptoms, exercise capacity, quality of life, these programs are underutilized due to barriers such as distance from rehabilitation centers, travel difficulties, cost, and time constraints. Hybrid based PR, which combines supervised in-center based sessions and tele-rehabilitation, offers a promising alternative to potentially overcome these limitations and improve patient engagement. There is a need to explore whether hybrid PR models can achieve comparable improvements in dyspnea, exercise capacity and quality of life in patients with post tubercular sequelae patients. A significant research gap exists regarding the application and validation of hybrid PR in this population. Evidence specifically supporting the effectiveness and optimal implementation of PR-particularly hybrid based models- in the context of post-tubercular sequelae remains limited. This research gap necessitates investigation into the feasibility and efficacy of hybrid PR to address the unique needs of individuals with Post-tubercular sequelae, considering the heterogeneity of the condition and the need for tailored interventions. Ultimately, evidence-based research in this area is crucial to develop accessible and effective rehabilitation strategies that can improve long-term outcomes and enhance the quality of life for TB survivors living with the sequelae of the disease.

研究设计

研究类型
Interventional
分配方式
Na
盲法
None

入排标准

年龄范围
18.00 Year(s) 至 65.00 Year(s)(—)
性别
All

入选标准

  • 1.Adult patients 18-65 years.
  • 2.Both male and female individuals.
  • 3.History of treated pulmonary tuberculosis.
  • 4.Diagnosed post tubercular sequelae (fibrotic and bronchiectasis variant) by high resolution computed tomography or chest x-ray.
  • 5.Shortness of breath (mMRC greater than 2).

排除标准

  • 1.Active tuberculosis infection.
  • 2.Hemoptysis.
  • 3.Patients with severe neurological, musculoskeletal, rheumatologic conditions affecting functional testing.
  • 4.Severe pulmonary hypertension.
  • 5.No participants in pulmonary rehabilitation in the last 6 months.
  • 6.Co-existing respiratory diseases (lung cancer).
  • 7.Unstable cardiac conditions (Unstable angina or recent MI).
  • 8.Severe obstruction less then 30 percentage of FVC and FEV
  • 9.Recent thoracic surgery (less than 3months).

研究者

发起方
KMCH College of Physiotherapy
申办方类型
Research institution and hospital
责任方
Principal Investigator
主要研究者

Manish Kumar S

KMCH College of Physiotherapy

研究点 (1)

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