REAL_PD - REAL_PD

niversitair Medisch Centrum Sint Radboud0 个研究点目标入组 20 人开始时间: 待定最近更新: 2024年4月23日

适应症

试验速览

暂无简介。

•- Dutch Parkinson patients
•- Male or female
•- Age 30 years or older at time of PD diagnosis
•- Subjects must have at least two of the following: resting tremor, bradykinesia, rigidity (must have either resting tremor or bradykinesia); OR either asymmetric resting tremor or asymmetric bradykinesia
•- Ability to provide written informed consent in accordance with Good Clinical Practice (GCP), International Conference on Harmonization (ICH), and local regulations

•- Little or no response to adequate doses of levodopa or a dopamine agonist
•- Atypical PD syndromes due to either drugs (e.g., metoclopramide, flunarizine, neuroleptics) or metabolic disorders (e.g., Wilson*s disease), encephalitis, or degenerative diseases (e.g., progressive supranuclear palsy)
•- A clinical diagnosis of dementia as determined by the investigator
•- Any other medical or psychiatric condition or lab abnormality, which in the opinion of the investigator might preclude participation
•- Previously obtained CT MRI scan is suggestive of another cause of parkinsonism, or with evidence of clinically significant other neurological disorder (in the opinion of the investigator)

发起方

niversitair Medisch Centrum Sint Radboud