IRCT20130418013058N17
尚未招募
2 期
Investigating the effect of crocin on the severity of fatigue, pain and quality of life in patients with multiple sclerosis
概览
- 阶段
- 2 期
- 干预措施
- 未指定
- 疾病 / 适应症
- 未指定
- 发起方
- Mashhad University of Medical Sciences
- 入组人数
- 40
- 状态
- 尚未招募
- 最后更新
- 2年前
概览
简要总结
暂无简介。
研究者
入排标准
入选标准
- •Definitive diagnosis of MS with neurologist visit, based on the McDonald diagnostic criteria, at least 6 months have passed since the diagnosis.
- •Patients with relapsing\-remitting MS or RRMS receiving first\- and second\-line MS disease therapy.
- •No relapse attacks one month before of the study.
- •Expression of willingness to participate in the study.
- •0 to 5 points based on expanded disability status scale.
- •?a fatigue intensity score equal to or higher than 4 according to the Fatigue severity scale
- •Having a feeling of chronic pain in at least one of the body organs and a score higher than 4 based on Numerical rating scale.
- •MS patients who take first and second line drugs (dimethyl fumarate, Resigen, Betaferon, Triflunomide, Fingolimido Cinomer).
排除标准
- •Suffering from other diseases such as (chronic diseases, heart failure, glands, breathing, liver, kidney, skeletal\-muscular) and mental diseases and severe depression.
- •Addiction to alcohol, drugs and psychedelics
- •History of allergy to saffron
- •Pregnancy and breastfeeding
- •The presence of severe infection and inflammation, varicose veins, active thrombosis, damage to organs such as fractures.
- •Motor disability score higher than 6
- •Getting any other serious diseases such as heart, liver and kidney diseases during treatment
- •Do heavy exercise daily
- •Any use of anti\-inflammatory and antioxidant drugs as a supplement or Amantadine as an anti\-fatigue drug
- •Unwillingness to participate in the study or continue the treatment process
结局指标
主要结局
未指定
相似试验
招募中
2 期
Evaluation of the effect of crocin in the treatment of cystoid macular edema secondary to retinitis pigmentosaIRCT20201219049753N2Mashhad University of Medical Sciences20
招募中
2 期
Evaluation of the effect of crocin on prevention of atrial fibrillation after heart surgeryIRCT20120520009801N4Mashhad University of Medical Sciences80
招募中
3 期
Therapeutic effect of crocin along with chemotherapy regimens in breast cancerBreast cancer.Malignant neoplasm of breast of unspecified siteC50.9IRCT20131017015044N3Mashhad University of Medical Sciences100
招募中
2 期
Evaluation of crocin in patients with refractory focal epilepsyIRCT20130418013058N16Mashhad University of Medical Sciences40
已完成
2 期
Effect of crocin supplementation in treatment of methadone maintenance treatment patientsAddiction.Mental and behavioural disorders due to multiple drug use and use of other psychoactive substancesIRCT20170420033551N4Kashan University of Medical Sciences60