IRCT20130418013058N17尚未招募2 期
Investigating the effect of crocin on the severity of fatigue, pain and quality of life in patients with multiple sclerosis
适应症
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 入组人数
- 40
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 years 至 50 years（—）
- 性别
- All
入选标准
- •Definitive diagnosis of MS with neurologist visit, based on the McDonald diagnostic criteria, at least 6 months have passed since the diagnosis.
- •Patients with relapsing-remitting MS or RRMS receiving first- and second-line MS disease therapy.
- •No relapse attacks one month before of the study.
- •Expression of willingness to participate in the study.
- •0 to 5 points based on expanded disability status scale.
- •?a fatigue intensity score equal to or higher than 4 according to the Fatigue severity scale
- •Having a feeling of chronic pain in at least one of the body organs and a score higher than 4 based on Numerical rating scale.
- •MS patients who take first and second line drugs (dimethyl fumarate, Resigen, Betaferon, Triflunomide, Fingolimido Cinomer).
排除标准
- •Suffering from other diseases such as (chronic diseases, heart failure, glands, breathing, liver, kidney, skeletal-muscular) and mental diseases and severe depression.
- •Addiction to alcohol, drugs and psychedelics
- •History of allergy to saffron
- •Pregnancy and breastfeeding
- •The presence of severe infection and inflammation, varicose veins, active thrombosis, damage to organs such as fractures.
- •Motor disability score higher than 6
- •Getting any other serious diseases such as heart, liver and kidney diseases during treatment
- •Do heavy exercise daily
- •Any use of anti-inflammatory and antioxidant drugs as a supplement or Amantadine as an anti-fatigue drug
- •Unwillingness to participate in the study or continue the treatment process
研究者
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