Comparison of Ultrasound Guided Pulsed Radiofrequency Versus Hyaluronidase Hydrodissection for Treatment of Carpal Tunnel Syndrome, a Prospective, Randomized, Controlled Clinical Study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 56
- 试验地点
- 1
- 主要终点
- Onset time of significant pain relief
研究概览
简要总结
The aim of this study is to compare the clinical efficacy and safety of ultrasound-guided pulsed radiofrequency and hyaluronidase hydrodissection in the treatment of carpal tunnel syndrome. This research seeks to evaluate both techniques in terms of pain relief, functional improvement, nerve conduction parameters, and potential complications, in order to identify the more effective minimally invasive approach for managing carpal tunnel syndrome.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adults aged 20-80 years
- •Clinical diagnosis of CTS with symptoms for at least 3 months
- •Electrophysiological evidence of mild to moderate CTS
- •No previous intervention for CTS in the affected hand
排除标准
- •Previous wrist surgery or trauma
- •Medical history of polyneuropathy, thoracic outlet syndrome, or brachial plexopathy
- •Coagulopathy or local infection at injection site
- •Pregnancy or breastfeeding
结局指标
主要结局
Onset time of significant pain relief
时间窗: 1 month
The VAS will be used to quantify pain on the scale of 0 (no pain) to 10 (extremely severe pain). Onset time will be defined as the day when the VAS score declined by 40% or more
次要结局
- Boston Carpal Tunnel Syndrome Questionnaire (BCTQ)(1 week and 1, 3, 6 months)
- Cross-sectional area (CSA)(baseline and then at 1-, 3-, and 6-months)
- Sensory nerve conduction velocity (SNCV)(baseline and 1, 3, and 6months post-injection)
研究者
Amany Mahmoud Mohamed
Resident of Anesthesia, ICU and Pain management faculty of medicine, Sohag University
Sohag University