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Vitamin D uptake in chronic kidney disease

Not Applicable
Recruiting
Conditions
N18
Chronic kidney disease
Registration Number
DRKS00029157
Lead Sponsor
niversitätsklinikum der RWTH Aachen
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
20
Inclusion Criteria

• stable, chronic hemodialysis patients
• Age of = 18 years
• Written informed consent prior to study participation
• The subject is willing and able to follow the procedures outlined in the protocol

Control group:
• Normal renal function
• Age- and sex-matched as well as written informed consent prior to study participation
• The subject is willing and able to follow the procedures outlined in the protocol

Exclusion Criteria

• Age less than 18 years
• Severe medical events within the last month
• Planned surgery within the duration of the sampling
• Acute/chronic gastrointestinal infections
• Recent or ongoing antibiotic therapy
• Conditions that impair vitamin D uptake or metabolism (chronic inflammatory bowel disease)
• Severe dyslipidemia
• Severe anemia, defined as hemoglobin level less than 9.0 g/dl
• Pregnant and lactating females
• Committed to an institution by legal or regulatory order
• Participation in a parallel interventional clinical trial
• Receipt of an investigational drug within 30 days prior to inclusion into this study
• The subject is mentally or legally incapacitated
• Vitamin D supplementation

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Determination of vitamin D content in lipoproteins up to 96h after ingestion
Secondary Outcome Measures
NameTimeMethod
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