A clinical trial to study effect of local injection of vitamin D3 on rate of tooth movement in patients undergoing fixed orthodontic treatment.
Phase 4
Not yet recruiting
- Conditions
- Health Condition 1: M263- Anomalies of tooth position of fully erupted tooth or teeth
- Registration Number
- CTRI/2020/09/027568
- Lead Sponsor
- Govt Dental College and Hospital Mumbai
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients with class I malocclusion with bimaxillary protrusion or class II malocclusion who require bimaxillary 1st premolar extraction.
Bimaxillary canine distalisation / retraction
Exclusion Criteria
Periodontally compromised patients.
No previous history of orthodontic treatment.
Subjects with crowded arches.
Subjects with parafunctional habits such as bruxism, & unilateral chewing pattern.
Subjects with nonvital , endodontically treated teeth, fractured teeth except Ellis class I & class II.
History of chronic drug intake.( anti inflammatory drugs, steroids over the prior 3 months.)
Medically compromised patients
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method rate of orthodontic tooth movementTimepoint: pre treatment i.e at the initiation of canine distalization <br/ ><br>post treatment i.e 60 days after 1st intraligamentary (PDL) injection of calcitriol
- Secondary Outcome Measures
Name Time Method Periapical & periradicular reaction( root resorption, bone loss , PDL space, continuity of lamina dura) to locally injected calcitriolTimepoint: Pre treatment i.e at the initiation of canine distalization <br/ ><br>Mid treatment i.e 60 days after 1st intraligamentary (PDL) injection of calcitriol