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临床试验/NCT05545176
NCT05545176招募中不适用

The Validation and Development of Termination-of-Resuscitation (TOR) Rules in Patients Following Out-of-Hospital Cardiac Arrest (OHCA) in Asia Countries

National Taiwan University Hospital1 个研究点 分布在 1 个国家目标入组 140,000 人开始时间: 2007年1月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
招募中
入组人数
140,000
试验地点
1
主要终点
survival to hospital discharge

研究概览

简要总结

Objectives/Hypotheses

  1. Prehospital termination-of-resuscitation (TOR) rules were developed in North American and European sites. Whether they remained valid in different geographic, ethnic, and cultural background areas is still under debate.
  2. Differences in characteristics of out-of-hospital cardiac arrests (OHCAs) and configurations of emergency medical service (EMS) between the Western and Asian countries, including relatively lower rate of presenting shockable rhythm (i.e. ventricular fibrillation / ventricular tachycardia; VF/VT), lower rates of bystander CPR, less advanced life support (ALS) implementation, and less public access defibrillators, might create potential threats to the prediction accuracy of TOR rules.
  3. We aim to conduct a study to validate the performance of ever published TOR rules in Asian OHCA population, including non-traumatic, traumatic, and pediatric OHCA patients. Furthermore, assess the possible variables that may impact the performance of TOR rules.
  4. We also aim to develop new TOR rules based on PAROS registry for Asia population, focusing on non-traumatic, traumatic, and pediatric OHCA patients, respectively.

研究设计

研究类型
Observational
观察模型
Other
时间视角
Other

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • out of hospital cardiac arrest (OHCA) patients

排除标准

  • age <18 years
  • non-EMS transport to the emergency department
  • obvious signs of death (e.g. decapitation, rigor mortis, lividity, and decapitation) or having do-not-resuscitate (DNR) orders
  • missing data despite meeting the inclusion criteria.

研究组 & 干预措施

out of hospital cardiac arrest patients in Asia countries

干预措施: termination of resuscitation rules (Other)

结局指标

主要结局

survival to hospital discharge

时间窗: survival to 30-day hospitalisation

survival to 30-day hospitalisation

次要结局

  • Cerebral Performance Categories Scale (CPC)(CPC within 30-day hospitalisation)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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