Investigating the obesity paradox in Chronic Obstructive Pulmonary Disease (COPD)

Not Applicable

Recruiting

• Conditions: Chronic Obstructive Pulmonary Disease; Obesity; Respiratory - Chronic obstructive pulmonary disease; Diet and Nutrition - Obesity

• Registration Number: ACTRN12612000056897
• Lead Sponsor: John Hunter Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2012-01-11
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 33

Inclusion Criteria

*Diagnosed COPD defined by a post bronchodilator FEV1 < 80% predicted and FER < 0.70
*Obesity defined by a BMI > 30kg/m2
*Satisfactory written and verbal English language skills.
*Willing and able to attend study visits

Exclusion Criteria

*Significant co-morbidity that the study visits may impact on
*Current smoker (smoked within the past 6 months);
*Pregnancy or breastfeeding;
*Taking insulin;
*A medical condition requiring a specialised dietary plan
*Cardiac arrhythmia, angina, congestive heart failure
*Renal or hepatic failure;
*Current gallstones
*Pancreatitis;
*Oedema
*Systemic disease (such as cancer);
*Change in medications or weight (+/- 5% body weight) in the previous 3 months; and
*Orthopaedic problems that would compromise the capacity to perform exercise.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
High sensitivity C-reactive protein measured by ELISA[0 and 12 weeks]