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临床试验/NCT07712211
NCT07712211招募中不适用

The Relationship Between Pain Catastrophizing Scale and Postoperative Nausea and Vomiting in Patients Undergoing Laparoscopic Cholecystectomy

Trabzon Kanuni Education and Research Hospital1 个研究点 分布在 1 个国家目标入组 64 人开始时间: 2026年1月15日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
64
试验地点
1
主要终点
Incidence of postoperative nausea and vomiting (PONV)

研究概览

简要总结

This study aims to explore whether patients' tendency to exaggerate or focus on pain (pain catastrophizing) is related to experiencing nausea and vomiting after surgery. The study will include patients undergoing laparoscopic cholecystectomy. Before surgery, patients will answer questions measuring pain catastrophizing and rate their pain during intravenous cannulation. Nausea and vomiting will be assessed at various times during the first 24 hours after surgery. The results may help better understand how psychological factors affect postoperative symptoms.

详细描述

This study is designed as a prospective, cross-sectional, and observational study. The Pain Catastrophizing Scale (PCS) is a well-established self-report instrument developed to assess catastrophic thinking related to pain. It evaluates how individuals perceive and respond to pain, focusing on tendencies such as rumination, magnification, and feelings of helplessness. Evidence suggests that PCS is a strong predictor of pain intensity, independent of anxiety levels. In this study, the validated Turkish version of the Pain Catastrophizing Scale will be used.

Postoperative nausea, vomiting, and retching are common adverse events that can complicate recovery from anesthesia. Patients often perceive these symptoms as more distressing than postoperative pain, and they represent important outcomes affecting patient satisfaction and recovery.

The present study aims to investigate the relationship between pain perception during intravenous (IV) cannulation, pain catastrophizing levels, and postoperative nausea and vomiting. By evaluating numeric pain scores during IV access alongside PCS scores, this study seeks to explore whether preoperative pain perception and psychological factors are associated with the frequency of postoperative nausea and vomiting.

The findings of this study are expected to contribute to a better understanding of the role of psychological factors in postoperative symptoms and may help improve anesthesia practices by supporting more individualized, patient-centered perioperative care.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Adult patients aged 18-65 years
  • American Society of Anesthesiologists (ASA) physical status I-II-III
  • Scheduled for elective laparoscopic cholecystectomy
  • Able to provide informed consent

排除标准

  • Age <18 or >65 years
  • Emergency surgery
  • ASA physical status > III
  • Pregnancy
  • Chronic opioid use
  • Known drug allergy
  • Psychiatric disorders
  • Neurological diseases (central or peripheral neuropathy)
  • History of cerebrovascular disease (stroke)
  • Chronic renal disease
  • Chronic pulmonary disease
  • Patients who refuse to participate

结局指标

主要结局

Incidence of postoperative nausea and vomiting (PONV)

时间窗: Within 24 hours postoperatively

The primary outcome is the incidence of postoperative nausea and vomiting (PONV) according to preoperative Pain Catastrophizing Scale (PCS) scores. Patients will be evaluated for PONV at 0, 3, 6, 12, and 24 hours postoperatively. The relationship between PCS scores and the frequency of PONV will be analyzed.

次要结局

  • Association between IV cannulation pain and pain catastrophizing(Preoperative period)

研究者

发起方
Trabzon Kanuni Education and Research Hospital
申办方类型
Other
责任方
Sponsor

研究点 (1)

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