跳至主要内容
临床试验/NCT03837886
NCT03837886Unknown不适用

Sodium Bicarbonate Supplementation Promotes Changes in Performance, Muscle Activity and Strength of Individuals Trained During the Performance of Intermittent and Intense Task? Randomized, Double-blind, Crossover Trial

University of Nove de Julho2 个研究点 分布在 1 个国家目标入组 12 人开始时间: 2019年10月20日最近更新:
适应症
干预措施

试验速览

阶段
不适用
入组人数
12
试验地点
2
主要终点
Electromyographic activity of the femoral quadriceps evaluated with electromyography equipment

研究概览

简要总结

The aim of this study was to verify if sodium bicarbonate (NaHCO3) suplementation promotes changes in the performance, muscular activity and strength of individuals trained during the intermittent and intense task . Twelve trained adult men will participate in this randomized, double-blind, crossover clinical trial. Each participant should receive two types of intervention with a 14-day interval between conditions: alkalosis (ALK) in which gelatinous capsules containing 0.3 g.kg -1 of NaHCO 3 and placebo (PLA) are administered, in which 0.3 g.kg-1 of Calcium Carbonate (CaCO3). The following results will be considered: electromyographic activity (EMG) of the quadriceps muscle, peak torque, pH, lactate, and perception of effort, recovery and pain questionnaires, which will be collected during intermittent and high intensity DI protocol. ANOVA of repeated measures will be used to verify possible differences between groups.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Other
盲法
Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)

入排标准

年龄范围
20 Years 至 42 Years(Adult)
性别
Male
接受健康志愿者

入选标准

  • resistance trained men (minimum 12 moths resistance training experience)

排除标准

  • diabetes mellitus;
  • respiratory (asthma, COPD), renal, metabolic, rheumatic and cardiovascular disorders;
  • acid-base balance disorder;
  • continuous use of some type of medication;
  • use of high-protein supplementation and creatine supplementation;
  • users of anabolic steroids.

研究组 & 干预措施

Alkalosis group

Experimental

The subjects should receive gelatinous capsules containing 0.3 g.kg -1 of sodium bicarbonate

干预措施: Sodium bicarbonate (Dietary Supplement)

Placebo group

Placebo Comparator

The subjects should receive gelatinous capsules containing 0.3 g.kg -1 of Calcium Carbonate

干预措施: Calcium carbonate (Dietary Supplement)

结局指标

主要结局

Electromyographic activity of the femoral quadriceps evaluated with electromyography equipment

时间窗: 60 minutes

The electromyographic activity will be obtained during the execution of 10 series composed of ten repetitions of extension (concentric phase) and flexion (eccentric phase) of the knee joint, at an angular velocity of 120os-1 (radians per second), with interval of 1 minute interval between sets in an isokinetic dynamometer.

Peak torque assessed with isokinetic dynamometer equipment

时间窗: 60 minutes

The peak torque will be obtained during the execution of 10 series composed of ten repetitions of extension (concentric phase) and flexion (eccentric phase) of the knee joint, at an angular velocity of 120os-1 (radians per second), with interval of 1 minute interval between sets.

次要结局

  • Lactate assessed with portable lactometer(15 seconds)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Fabiano Politti

Principal Investigator

University of Nove de Julho

研究点 (2)

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