Ozone Dental Gel as an Adjunct to Non-Surgical Periodontitis Therapy: Clinical and Immunological Evaluatio
Phase 3
- Conditions
- PeriodontitisOzone gel, periodontal pocket, Periodontitis, Non-Surgical Periodontal Therapy
- Registration Number
- TCTR20240731002
- Lead Sponsor
- Hospital of stomatology of Sana'a University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending (Not yet recruiting)
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
1-An age group of 20 - 50 years .
2-Both sexes were included .
3- Patients with periodontitis .
4- Probing pocket depth. ( PPD) more than or equal to 5mm .
6- Patient without systematic disease .
Exclusion Criteria
1- subjects who had priorly taken antibiotics or were on antibiotics during the trial .
2- Medication taken by patients that would induce gingival enlargement .
3- pregnant women or lactating mothers .
4- Current smoker .
5- Patients with habit of Khat chewing .
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms does ozone dental gel utilize to modulate immune responses in periodontitis?
How does ozone gel compare to chlorhexidine in reducing periodontal pocket depth post-non-surgical therapy?
Which inflammatory biomarkers (e.g., IL-1β, TNF-α) correlate with ozone gel efficacy in Phase III periodontitis trials?
What adverse effects are associated with ozone gel application in periodontal pockets, and how are they managed?
Are there synergistic effects when combining ozone gel with laser therapy or photodynamic treatment for periodontitis?