A randomized, double-blind, active controlled, parallel-group, clinical study to evaluate the efficacy and safety of poly herb gel in treatment of clinically diagnosed stage I and Stage II Oral Sub Mucous Fibrosis.

There is multi drug concept in treating OSMF and use of steroids will have long term disadvantage. Disadvantage of intralesional injections can form more fibrous bands, mucosal atrophy, difficulty to deposit sufficient quantities into gingival lesions, injection are painful and intrusive.  Herbal medicine has been used for thousands of years to treat a variety of health issues. It’s generally gentler on the body and has fewer side effects than prescription drugs, and it can also be more affordable. The  World Health Organization guidelines define herbal  medicines as finished, labeled medicinal products containing an active ingredient, i.e.,  obtained from the aerial or underground parts of botanicals or other plant materials or  their combination.4   Hence using poly herb has medicinal or rasaya properties provide a synergestic effect in the treatment. It is also safer and more potent in long term. Starting a poly herbal gel improves prognosis of the disease