跳至主要内容
临床试验/NCT07546461
NCT07546461Enrolling By Invitation不适用

A Multiphase Operational and Environmental Assessment of Lunar Surface Habitation, Lunar Gateway Transit Systems, and Acceleration Pathways for Sustained Human Habitation of the Martian Surface

Truway Health, Inc.1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2026年6月26日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
Enrolling By Invitation
发起方
入组人数
30
试验地点
1
主要终点
Habitat System Resilience Index (HSRI)

研究概览

简要总结

This study evaluates the operational, environmental, and habitation-system requirements for sustained human presence on the lunar surface, the performance of the Lunar Gateway as a transit and staging architecture, and the pathways required to accelerate readiness for Martian surface habitation. The protocol examines habitat resilience, radiation exposure modeling, life-support continuity, EVA logistics, behavioral health in isolated environments, and systems-engineering workflows across lunar, transit, and Mars-analog environments. Special emphasis is placed on the identification, extraction, processing, and utilization of lunar water-ice deposits as a critical resource for life-support, radiation shielding, and in-situ propellant production. Findings will inform future mission design, habitation module development, and interplanetary operational frameworks.

详细描述

This multiphase observational and operational protocol investigates the habitation lifecycle across three mission environments: (1) lunar surface habitation systems, (2) Lunar Gateway transit architecture, and (3) Martian surface analog habitats. The study integrates engineering, environmental, behavioral, and operational assessments to characterize requirements for long-duration human habitation beyond Earth orbit, with a specific focus on the role of water-ice resources in sustaining habitation and enabling interplanetary logistics.

The lunar surface phase evaluates habitat stability, environmental control and life-support system (ECLSS) resilience, radiation shielding performance, EVA logistics, mobility constraints, and dust mitigation strategies. A central component of this phase is the assessment of lunar water-ice availability, extraction feasibility, thermal stability, and processing pathways. Water-ice is evaluated as a source for potable water, oxygen generation, hydrogen production, and in-situ propellant manufacturing. Operational workflows, redundancy models, and failure-mode responses are analyzed to determine the feasibility of sustained lunar habitation supported by local resource utilization.

The Lunar Gateway phase examines transit-architecture performance, including docking operations, crew systems behavior, resource transfer workflows, and the continuity of life-support and environmental systems during transit. The study evaluates how water-ice-derived consumables from the lunar surface could be staged, processed, or transferred through the Gateway to support outbound missions. Behavioral health observations and operational stressors are assessed to understand crew performance in confined transit environments.

The Martian surface analog phase focuses on long-duration isolation, dust intrusion mitigation, power redundancy, habitat resilience, and environmental stability under Mars-analog conditions. This phase evaluates the translational pathways required to accelerate readiness for Martian habitation, including the potential use of Martian subsurface ice deposits for life-support, radiation shielding, and fuel production. Comparisons between lunar and Martian ice-resource utilization inform cross-environment operational strategies.

Across all phases, the protocol collects operational, environmental, and systems-engineering data to inform future mission architectures, habitation module design, and interplanetary habitation strategies. The study does not involve FDA-regulated products, biomedical interventions, or human subjects research as defined by federal regulations. All activities occur within controlled operational and engineering environments.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Adults aged 18-65
  • Able to participate in isolated, confined, or controlled operational environments
  • Prior experience in engineering, environmental systems, analog missions, or mission operations
  • Ability to perform EVA-analog tasks and operational workflows
  • Willingness to participate in multi-phase lunar, transit, and Mars-analog simulations

排除标准

  • Medical or physical limitations that prevent participation in isolated or operational environments
  • Conditions that limit safe participation in EVA-analog tasks
  • Inability to comply with operational protocols or safety requirements
  • Participation in conflicting operational studies

研究组 & 干预措施

Lunar Surface Habitation Cohort

Participants assigned to evaluate lunar surface habitation systems, including habitat stability, ECLSS performance, radiation shielding, EVA logistics, and water-ice extraction workflows.

干预措施: Habitat Systems Evaluation (Other)

Lunar Gateway Transit Cohort

Participants assigned to assess Lunar Gateway transit operations, including docking workflows, resource transfer, life-support continuity, and staging of water-ice-derived consumables.

干预措施: Habitat Systems Evaluation (Other)

Lunar Gateway Transit Cohort

Participants assigned to assess Lunar Gateway transit operations, including docking workflows, resource transfer, life-support continuity, and staging of water-ice-derived consumables.

干预措施: Water-Ice Resource Utilization Assessment (Other)

Martian Surface Analog Cohort

Participants assigned to operate within Mars-analog habitats to evaluate long-duration isolation, dust mitigation, power redundancy, and utilization pathways for Martian subsurface ice.

干预措施: Habitat Systems Evaluation (Other)

Martian Surface Analog Cohort

Participants assigned to operate within Mars-analog habitats to evaluate long-duration isolation, dust mitigation, power redundancy, and utilization pathways for Martian subsurface ice.

干预措施: Water-Ice Resource Utilization Assessment (Other)

Martian Surface Analog Cohort

Participants assigned to operate within Mars-analog habitats to evaluate long-duration isolation, dust mitigation, power redundancy, and utilization pathways for Martian subsurface ice.

干预措施: EVA and Mobility Operations (Other)

Lunar Surface Habitation Cohort

Participants assigned to evaluate lunar surface habitation systems, including habitat stability, ECLSS performance, radiation shielding, EVA logistics, and water-ice extraction workflows.

干预措施: Water-Ice Resource Utilization Assessment (Other)

Lunar Surface Habitation Cohort

Participants assigned to evaluate lunar surface habitation systems, including habitat stability, ECLSS performance, radiation shielding, EVA logistics, and water-ice extraction workflows.

干预措施: EVA and Mobility Operations (Other)

结局指标

主要结局

Habitat System Resilience Index (HSRI)

时间窗: 36 months

HSRI is a composite scale (0-100) assessing environmental stability, ECLSS uptime (%), redundancy activation success rate (%), and mean time to recovery (hours). Higher scores indicate better habitat resilience.

Water-Ice Utilization Efficiency Ratio

时间窗: 36 months

Efficiency ratio (%) measured using the Water-Ice Processing Performance Scale (WIPPS; 0-100%), quantifying the proportion of extracted ice converted into usable water, oxygen, hydrogen, and propellant. Higher values indicate greater efficiency.

Radiation Modeling Accuracy Score

时间窗: 36 months

Accuracy score (%) comparing predicted radiation dose (mSv) to measured dose using the Habitat Radiation Monitoring System (HRMS). Higher scores indicate greater predictive accuracy.

次要结局

  • EVA Task Completion Time(36 months)
  • EVA Mobility Constraint Score(36 months)
  • Dust Intrusion Index(36 months)
  • Life-Support Continuity Score (LSCS)(36 months)
  • Behavioral Health Stability Index (BHSI)(36 months)
  • Power System Uptime Percentage(36 months)
  • Redundancy Activation Success Rate(36 months)
  • Power Recovery Time(36 months)
  • Particulate Intrusion Reduction Score(36 months)
  • Abrasion Resistance Index(36 months)
  • Operational Degradation Rate(36 months)
  • Transit-to-Surface Operational Continuity Score (TSOCS)(36 months)

研究者

发起方
Truway Health, Inc.
申办方类型
Industry
责任方
Sponsor

研究点 (1)

Loading locations...

相似试验

进行中(未招募)
不适用
A Phase IV, Multi-Center, Active-Controlled, Observer-Blind Study to Evaluate the Safety of a Trivalent Subunit Influenza Vaccine Produced either in Mammalian Cell Culture (Optaflu®) or in Embryonated Hen Eggs (Agrippal®) in Adults and Elderly With and Without Underlying Medical Conditions, and to Evaluate the Immunogenicity in a Subset of Subjects With Underlying Medical Conditions.no medical condition: healthy subjects
EUCTR2007-002872-32-DEovartis Vaccines and Diagnostics S.r.l.
进行中(未招募)
不适用
An open, multi-centre, phase IIIb, long term follow-up study to assess the safety, tolerability and efficacy of once-daily oral modified-release hydrocortisone in patients with adrenal insufficiency.
EUCTR2008-003990-42-SEDuoCort Pharma AB86
进行中(未招募)
1 期
Safety and Efficacy of peripheral blood stem cell transplantation using specifically purified stem cell preparations derived from patient family members in paediatric and adult patientsHematological and non-hematological malignancies, and non-malignant diseases, requiring allogeneic blood stem cell transplantation without available HLA-identical donor.MedDRA version: 18.1 Level: PT Classification code 10063581 Term: Stem cell transplant System Organ Class: 10042613 - Surgical and medical procedures
EUCTR2011-005562-38-DEMiltenyi Biotec GmbH60
进行中(未招募)
1 期
Safety and Efficacy of peripheral blood stem cell transplantation using specifically purified stem cell preparations derived from patient family members in paediatric and adult patientsHematological and non-hematological malignancies, and non-malignant diseases, requiring allogeneic blood stem cell transplantation without available HLA-identical donor.MedDRA version: 18.1 Level: PT Classification code 10063581 Term: Stem cell transplant System Organ Class: 10042613 - Surgical and medical procedures
EUCTR2011-005562-38-NLMiltenyi Biotec GmbH60
进行中(未招募)
1 期
A PHASE 3, MULTICENTER, LONG-TERM OBSERVATIONAL STUDY OF SUBJECTS FROM TANEZUMAB STUDIES WHO UNDERGO A TOTAL KNEE, HIP OR SHOULDER REPLACEMENT
EUCTR2013-002549-12-GBPfizer Inc.,211