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Comparison of organs at risk and target volumes using MRI and CT scan in head and neck malignancy radiation treatment planning

Not Applicable
Completed
Conditions
ewly diagnosed biopsy-proven head and neck malignancy
Cancer
Registration Number
ISRCTN34023049
Lead Sponsor
All India Institute of Medical Sciences, Rishikesh
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
54
Inclusion Criteria

1. Newly diagnosed biopsy-proven head and neck cancer
2. Age over 18 years
3. Eastern Co-operative Oncology Group (ECOG) performance status of 0- 2
4. Normal kidney function test

Exclusion Criteria

1. Poor performance status of ECOG 3-4
2. Deranged serum creatinine and blood urea
3. Presence of metal elements in patient’s body that are MRI incompatible
4. Allergy to CT or MRI contrast
5. Second primary/recurrent head and neck cancer
6. Patients who have undergone tracheostomy

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Concordance in CT and MRI contouring of target volumes and organs at risk, measured using the Dice Similarity Coeffcient, Conformity Index, Sensitivity Index, and Inclusion Index, calculated at the time of contouring
Secondary Outcome Measures
NameTimeMethod
There are no secondary outcome measures
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