Effect Of Vaginal Cream Glycyrrihiza Glabra On Improvement Of Symptoms Of Fungal Vulvovaginitis

Phase 2

• Conditions: candidal vulvovaginitis.; Candidiasis of vulva and vagina

• Registration Number: IRCT2017031133008N1
• Lead Sponsor: Vice chancellor for research of Iran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 60

Inclusion Criteria

Including criteria consisted of: Women at reproductive age of 15 to 45 years old ?. married ?. not being pregnant, menopause, and breast feeding ?. having at least two symptoms of vaginal candidiasis in interview( observed and being confirmed by laboratory studies) ?. Lack of chronic diseases such as disorders that weaken the immune system, blood pressure, and diabetes ?. no use of Chemical and herbal antifungal drugs during the last two weeks ?. not having other vaginal infection such as trichomonas vaginitis, bacterial and mixtures ?. not using vaginal creams and suppositories during the 48 hours before starting of the study ?. not participating in another research study, simultaneously with this study ?. lack of allergy to licorice ?. lack of use of broad-spectrum antibiotics and corticosteroids during the last two weeks for any medical proposes .
Exclusion criteria consisted of: getting pregnant during the study ?. allergy to licorice ?. obligation to use of antibiotics for treatment of systemic infections other than vaginitis during the study ?. Failure to adhere to the correct pattern of the treatment (forgetting the drug for more than one night).

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Vaginal sores and lesions. Timepoint: 1,7,14day. Method of measurement: positive,negetive.;Vaginal redness. Timepoint: 1,7,14day. Method of measurement: positive,negetive.;Itching genitals. Timepoint: 1,7,14. Method of measurement: positive,negetive.;Dysuria. Timepoint: 1,7,14 day. Method of measurement: positive,negetive.;Cheesy white secretions. Timepoint: 1,7,14day. Method of measurement: positive,negetive.;Dyspareunia. Timepoint: 1,7,14. Method of measurement: positive,negetive.;Red vagina is with white discharge. Timepoint: 1,7,14day. Method of measurement: positive,negetive.;Papulopustular damagesand. Timepoint: 1,7,14. Method of measurement: positive,negetive.;Abnormal cervical. Timepoint: 1,7,14day. Method of measurement: positive,negetive.;Laboratory evaluation. Timepoint: 1,7,14day. Method of measurement: positive,negetive.

Secondary Outcome Measures

Name	Time	Method
icorice sensitivity. Timepoint: 1,7,14. Method of measurement: positive,negetive.