Nasopharyngeal 24 Hour pH Monitoring in Health Adult Volunteers
Not Applicable
Withdrawn
- Conditions
- Gastroesophageal Reflux Disease
- Registration Number
- NCT00584675
- Lead Sponsor
- University of California, Davis
- Brief Summary
Involves a 24-hour pH probe study using the Dx-pH Measurement System on patients who do not have symptoms of laryngopharyngeal reflux or gastroesophageal reflux disease to establish normal values for the Dx-pH Measurement System.
- Detailed Description
The specific aim of this study is to establish the normal range of values in an adult population with no symptoms of laryngopharyngeal reflux disease or gastroesophageal reflux disease using the Dx-pH Measurement System.
Recruitment & Eligibility
- Status
- WITHDRAWN
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
- 18 years of age or older
- no symptoms of laryngopharyngeal reflux or gastroesophageal reflux disease
- score less than 10 on Reflux Symptom Index
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Exclusion Criteria
- age less than 18
- known lidocaine allergy
- history of heartburn, regurgitation, chronic cough, voice changes, globus pharyngeus, excessive throat clearing, or swallowing problems
- score 10 or greater on Reflux Symptom Index
- current or past antacid use or other antireflux therapy
- history of antireflux surgery
- pregnancy
- current anticoagulation therapy (warfarin, heparin, aspirin, clopidogrel bisulfate)
- special/vulnerable populations (children, mentally handicapped, pregnant women, fetuses, prisoners, cognitive impairment, life-threatening disease, social or economic disadvantage)
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Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method To develop a range of normal values in adults without symptoms of laryngopharyngeal reflux. At completion of study
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
University of California Davis Medical Center
🇺🇸Sacramento, California, United States